DIO1 protein (Felis catus) - STRING interaction network

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DIO1

Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney. (244 aa)

Predicted Functional Partners:

DIO2

0.964

SELENOK

0.582

SELENOT

0.582

SELENOH

0.579

HPRT1

0.499

WSB1

0.487

DAB2IP

0.485

TXNRD1

0.450

RAB17

0.445

CDH16

0.444

Your Current Organism:

Felis catus

NCBI taxonomy Id: 9685
Other names: F. catus, Felis domesticus, Felis silvestris catus, Korat cats, cat, cats, domestic cat

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH16	DIO1	ENSFCAP00000047128	ENSFCAP00000021400	Cadherin 16.	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	0.444
DAB2IP	DIO1	ENSFCAP00000028617	ENSFCAP00000021400	DAB2 interacting protein.	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	0.485
DIO1	CDH16	ENSFCAP00000021400	ENSFCAP00000047128	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	Cadherin 16.	0.444
DIO1	DAB2IP	ENSFCAP00000021400	ENSFCAP00000028617	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	DAB2 interacting protein.	0.485
DIO1	DIO2	ENSFCAP00000021400	ENSFCAP00000029280	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).	0.964
DIO1	HPRT1	ENSFCAP00000021400	ENSFCAP00000060001	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	0.499
DIO1	RAB17	ENSFCAP00000021400	ENSFCAP00000028528	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	RAB17, member RAS oncogene family.	0.445
DIO1	SELENOH	ENSFCAP00000021400	ENSFCAP00000033535	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	Selenoprotein H.	0.579
DIO1	SELENOK	ENSFCAP00000021400	ENSFCAP00000005222	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	Selenoprotein K.	0.582
DIO1	SELENOT	ENSFCAP00000021400	ENSFCAP00000036165	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily.	0.582
DIO1	TXNRD1	ENSFCAP00000021400	ENSFCAP00000061137	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	Thioredoxin reductase 1; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.450
DIO1	WSB1	ENSFCAP00000021400	ENSFCAP00000057345	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	WD repeat and SOCS box containing 1.	0.487
DIO2	DIO1	ENSFCAP00000029280	ENSFCAP00000021400	Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	0.964
DIO2	WSB1	ENSFCAP00000029280	ENSFCAP00000057345	Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine).	WD repeat and SOCS box containing 1.	0.582
HPRT1	DIO1	ENSFCAP00000060001	ENSFCAP00000021400	Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family.	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	0.499
RAB17	DIO1	ENSFCAP00000028528	ENSFCAP00000021400	RAB17, member RAS oncogene family.	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	0.445
SELENOH	DIO1	ENSFCAP00000033535	ENSFCAP00000021400	Selenoprotein H.	Type I iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.	0.579
SELENOH	SELENOK	ENSFCAP00000033535	ENSFCAP00000005222	Selenoprotein H.	Selenoprotein K.	0.843
SELENOH	SELENOT	ENSFCAP00000033535	ENSFCAP00000036165	Selenoprotein H.	Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily.	0.837
SELENOH	TXNRD1	ENSFCAP00000033535	ENSFCAP00000061137	Selenoprotein H.	Thioredoxin reductase 1; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.	0.745

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