STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORAOV1Oral cancer-overexpressed protein 1. (137 aa)    
Predicted Functional Partners:
YAE1D1
Yae1 domain-containing protein 1.
   
 
 0.947
ABCE1
ATP-binding cassette sub-family E member 1.
    
 
 0.855
PPFIA1
Liprin-alpha-1 isoform X1.
      
 0.611
MMS19
MMS19 nucleotide excision repair protein homolog isoform X1.
    
 
 0.551
PEBP4
LOW QUALITY PROTEIN: phosphatidylethanolamine-binding protein 4.
      
 0.522
HP
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidly cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway.
      
 0.451
ASIP
Agouti-signaling protein.
      
 0.449
SOX5
Transcription factor SOX-5 isoform X1.
      
 0.442
STX17
Syntaxin-17; Belongs to the syntaxin family.
      
 0.439
FGF4
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.438
Your Current Organism:
Odobenus rosmarus
NCBI taxonomy Id: 9708
Other names: O. rosmarus divergens, Odobenus rosmarus divergens, Pacific walrus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.