node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC101363266 | RNF8 | A0A2U3ZD45 | A0A2U3WLK5 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | 0.740 |
LOC101363266 | RPS27A | A0A2U3ZD45 | A0A2U3W6C1 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | ubiquitin-40S ribosomal protein S27a. | 0.819 |
LOC101363266 | UBA52 | A0A2U3ZD45 | A0A2U3ZJX2 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | ubiquitin-60S ribosomal protein L40 isoform X1. | 0.716 |
LOC101363266 | UBE2V2 | A0A2U3ZD45 | A0A2U3ZB83 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 variant 2 isoform X1. | 0.929 |
LOC101363416 | RNF8 | A0A2U3ZFF6 | A0A2U3WLK5 | Ubiquitin-conjugating enzyme E2 N-like. | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | 0.740 |
LOC101363416 | RPS27A | A0A2U3ZFF6 | A0A2U3W6C1 | Ubiquitin-conjugating enzyme E2 N-like. | ubiquitin-40S ribosomal protein S27a. | 0.819 |
LOC101363416 | UBA52 | A0A2U3ZFF6 | A0A2U3ZJX2 | Ubiquitin-conjugating enzyme E2 N-like. | ubiquitin-60S ribosomal protein L40 isoform X1. | 0.716 |
LOC101363416 | UBE2V2 | A0A2U3ZFF6 | A0A2U3ZB83 | Ubiquitin-conjugating enzyme E2 N-like. | Ubiquitin-conjugating enzyme E2 variant 2 isoform X1. | 0.929 |
LOC101369061 | RNF8 | A0A2U3ZR76 | A0A2U3WLK5 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | 0.929 |
LOC101369061 | RPS27A | A0A2U3ZR76 | A0A2U3W6C1 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | ubiquitin-40S ribosomal protein S27a. | 0.934 |
LOC101369061 | UBA52 | A0A2U3ZR76 | A0A2U3ZJX2 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | ubiquitin-60S ribosomal protein L40 isoform X1. | 0.716 |
LOC101369061 | UBE2V2 | A0A2U3ZR76 | A0A2U3ZB83 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 variant 2 isoform X1. | 0.983 |
LOC101369231 | RNF8 | A0A2U3W954 | A0A2U3WLK5 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | 0.740 |
LOC101369231 | RPS27A | A0A2U3W954 | A0A2U3W6C1 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | ubiquitin-40S ribosomal protein S27a. | 0.819 |
LOC101369231 | UBA52 | A0A2U3W954 | A0A2U3ZJX2 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | ubiquitin-60S ribosomal protein L40 isoform X1. | 0.716 |
LOC101369231 | UBE2V2 | A0A2U3W954 | A0A2U3ZB83 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 variant 2 isoform X1. | 0.929 |
LOC101376219 | RNF8 | A0A2U3ZFY5 | A0A2U3WLK5 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] | 0.740 |
LOC101376219 | RPS27A | A0A2U3ZFY5 | A0A2U3W6C1 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | ubiquitin-40S ribosomal protein S27a. | 0.819 |
LOC101376219 | UBA52 | A0A2U3ZFY5 | A0A2U3ZJX2 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | ubiquitin-60S ribosomal protein L40 isoform X1. | 0.716 |
LOC101376219 | UBE2V2 | A0A2U3ZFY5 | A0A2U3ZB83 | Ubiquitin-conjugating enzyme E2 N-like; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 variant 2 isoform X1. | 0.929 |