STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (475 aa)    
Predicted Functional Partners:
RCE1
CAAX prenyl protease 2-like isoform X1.
    
 0.961
FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha.
     
 0.943
FNTB
Protein farnesyltransferase subunit beta; Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.
     
 0.924
CHURC1
Protein Churchill isoform X1.
     
 0.672
LMNB1
lamin-B1; Belongs to the intermediate filament family.
    
 
 0.661
LMNA
prelamin-A/C isoform X1; Belongs to the intermediate filament family.
    
 
 0.611
SUN1
SUN domain-containing protein 1.
    
 
 0.598
GRPEL1
GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.
  
  
 0.584
GRPEL2
grpE protein homolog 2, mitochondrial.
  
  
 0.584
HSPE1
10 kDa heat shock protein, mitochondrial; Belongs to the GroES chaperonin family.
  
  
 0.561
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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