STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NKX2-1Homeobox protein Nkx-2.1. (252 aa)    
Predicted Functional Partners:
SFTPC
Pulmonary surfactant-associated protein C.
   
  
 0.796
LHX8
LIM/homeobox protein Lhx8 isoform X1.
   
  
 0.584
LHX6
LIM/homeobox protein Lhx6 isoform X2.
   
  
 0.584
FOXA1
Hepatocyte nuclear factor 3-alpha.
  
 
 0.581
FOXA2
Hepatocyte nuclear factor 3-beta-like.
   
 
 0.551
SST
Somatostatin.
      
 0.548
TSHR
Thyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
      
 0.540
LOC102747609
Pulmonary surfactant-associated protein A-like.
   
  
 0.518
LOC102727345
Transcription factor SOX-9-like.
    
 
 0.499
FGF10
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
      
 0.489
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
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