STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOTCH2Neurogenic locus notch homolog protein 2. (1238 aa)    
Predicted Functional Partners:
JAG1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.990
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.985
DLL1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
    
0.979
LFNG
beta-1,3-N-acetylglucosaminyltransferase lunatic fringe.
    
 0.962
NUMB
Protein numb homolog isoform X1.
    
 0.951
MAML1
Mastermind-like protein 1.
   
 0.948
MFNG
Beta-1,3-N-acetylglucosaminyltransferase.
    
 0.941
RBPJL
Recombining binding protein suppressor of hairless-like protein.
    
 0.932
NCSTN
Nicastrin.
    
 0.931
LOC102729516
Mastermind-like protein 2-like.
    
 0.914
Your Current Organism:
Leptonychotes weddellii
NCBI taxonomy Id: 9713
Other names: L. weddellii, Leptonychotes weddelli, Weddell seal
Server load: low (22%) [HD]