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ADAM17 protein (Tursiops truncatus) - STRING interaction network
"ADAM17" - ADAM metallopeptidase domain 17 in Tursiops truncatus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADAM17ADAM metallopeptidase domain 17 (829 aa)    
Predicted Functional Partners:
NOTCH2
Notch 2 (2471 aa)
     
  0.940
ADAM10
ADAM metallopeptidase domain 10 (729 aa)
     
 
0.874
SNED1
Sushi, nidogen and EGF-like domains 1 (1326 aa)
       
  0.754
ENSTTRG00000014085
Tumor necrosis factor Tumor necrosis factor, membrane form Tumor necrosis factor, soluble form (233 aa)
       
  0.705
EGFR
Epidermal growth factor receptor (1211 aa)
     
  0.661
EGF
Epidermal growth factor (1205 aa)
         
  0.652
HBEGF
Heparin-binding EGF-like growth factor (208 aa)
         
  0.641
NOTCH3
Notch 3 (2308 aa)
       
  0.607
SVEP1
Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (3575 aa)
       
  0.594
TIMP3
TIMP metallopeptidase inhibitor 3 (211 aa)
       
 
  0.582
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottle-nosed dolphin, Cetacea, Delphinidae, Odontoceti, T. truncatus, Tursiops, Tursiops truncatus, bottle-nosed dolphin, bottlenosed dolphin, dolphins, marine dolphins, tooth whales, whale, whales, whales & dolphins, whales, dolphins, and porpoises
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