STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
USP42Ubiquitin carboxyl-terminal hydrolase 42 isoform X2; Belongs to the peptidase C19 family. (1320 aa)    
Predicted Functional Partners:
TMTC2
Transmembrane and TPR repeat-containing protein 2.
      
 0.689
RCE1
Ras converting CAAX endopeptidase 1.
     
 0.683
ANKRD61
LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 61.
      
 0.681
SUDS3
Sin3 histone deacetylase corepressor complex component SDS3 isoform X3.
    
 0.680
TP53
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.594
KLHL18
Kelch like family member 18.
    
 
 0.593
CDC25A
M-phase inducer phosphatase 1 isoform X1.
    
 0.585
BRMS1L
Breast cancer metastasis-suppressor 1-like protein isoform X2.
    
  0.584
BRMS1
Breast cancer metastasis-suppressor 1 isoform X1.
    
  0.584
SLC25A21
Mitochondrial 2-oxodicarboxylate carrier isoform X2; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.579
Your Current Organism:
Tursiops truncatus
NCBI taxonomy Id: 9739
Other names: Atlantic bottlenose dolphin, T. truncatus, bottle-nosed dolphin, common bottlenose dolphin
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.