node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACVR1B | ACVR1C | ENSLAFP00000026010 | ENSLAFP00000017776 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.970 |
ACVR1B | SMAD2 | ENSLAFP00000026010 | ENSLAFP00000000114 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.962 |
ACVR1B | SMAD4 | ENSLAFP00000026010 | ENSLAFP00000010529 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Mothers against decapentaplegic homolog. | 0.733 |
ACVR1B | TGFBR1 | ENSLAFP00000026010 | ENSLAFP00000023233 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.664 |
ACVR1B | TGFBR2 | ENSLAFP00000026010 | ENSLAFP00000003159 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.775 |
ACVR1B | ZFYVE16 | ENSLAFP00000026010 | ENSLAFP00000014769 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Zinc finger FYVE domain-containing protein. | 0.405 |
ACVR1B | ZFYVE9 | ENSLAFP00000026010 | ENSLAFP00000007245 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | Zinc finger FYVE domain-containing protein. | 0.409 |
ACVR1C | ACVR1B | ENSLAFP00000017776 | ENSLAFP00000026010 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.970 |
ACVR1C | SMAD2 | ENSLAFP00000017776 | ENSLAFP00000000114 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Mothers against decapentaplegic homolog. | 0.955 |
ACVR1C | SMAD4 | ENSLAFP00000017776 | ENSLAFP00000010529 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Mothers against decapentaplegic homolog. | 0.577 |
ACVR1C | TGFBR1 | ENSLAFP00000017776 | ENSLAFP00000023233 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.543 |
ACVR1C | TGFBR2 | ENSLAFP00000017776 | ENSLAFP00000003159 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] | 0.775 |
ACVR1C | ZFYVE16 | ENSLAFP00000017776 | ENSLAFP00000014769 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Zinc finger FYVE domain-containing protein. | 0.405 |
ACVR1C | ZFYVE9 | ENSLAFP00000017776 | ENSLAFP00000007245 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | Zinc finger FYVE domain-containing protein. | 0.405 |
E2F4 | SMAD2 | ENSLAFP00000020043 | ENSLAFP00000000114 | E2F transcription factor 4. | Mothers against decapentaplegic homolog. | 0.955 |
E2F4 | SMAD4 | ENSLAFP00000020043 | ENSLAFP00000010529 | E2F transcription factor 4. | Mothers against decapentaplegic homolog. | 0.980 |
SMAD2 | ACVR1B | ENSLAFP00000000114 | ENSLAFP00000026010 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. | 0.962 |
SMAD2 | ACVR1C | ENSLAFP00000000114 | ENSLAFP00000017776 | Mothers against decapentaplegic homolog. | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. | 0.955 |
SMAD2 | E2F4 | ENSLAFP00000000114 | ENSLAFP00000020043 | Mothers against decapentaplegic homolog. | E2F transcription factor 4. | 0.955 |
SMAD2 | SMAD4 | ENSLAFP00000000114 | ENSLAFP00000010529 | Mothers against decapentaplegic homolog. | Mothers against decapentaplegic homolog. | 0.996 |