STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RHOARas homolog family member A. (193 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
    
 0.992
G3U095_LOXAF
Uncharacterized protein.
    
 0.992
ROCK1
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.983
ROCK2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
   
 0.976
ARHGAP35
Rho GTPase activating protein 35.
    
 0.975
ARHGEF28
Rho guanine nucleotide exchange factor 28.
   
 0.975
ARHGEF12
Rho guanine nucleotide exchange factor 12.
   
 0.973
ARHGEF11
Rho guanine nucleotide exchange factor 11.
   
 0.972
ARHGDIA
Rho GDP dissociation inhibitor alpha.
   
 0.971
ARHGDIB
Rho GDP dissociation inhibitor beta.
   
 0.971
Your Current Organism:
Loxodonta africana
NCBI taxonomy Id: 9785
Other names: African bush elephant, African savanna elephant, African savannah elephant, L. africana, Loxodonta africana africana, elephant
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.