STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPRK1Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (435 aa)    
Predicted Functional Partners:
PENK
Proenkephalin.
    
 0.973
POMC
Melanotropin beta; MSH (melanocyte-stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes; Belongs to the POMC family.
   
 0.971
PDYN
Prodynorphin.
   
 
 0.965
SST
Somatostatin.
    
 0.619
PNOC
Prepronociceptin.
   
 0.607
GAL
Galanin and GMAP prepropeptide.
    
 0.582
EBAG9
Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.
      
 0.570
GPR160
G protein-coupled receptor 160.
      
 0.569
SLC22A11
Solute carrier family 22 member 11.
      
 0.569
GPR142
G protein-coupled receptor 142; Belongs to the G-protein coupled receptor 1 family.
      
 0.547
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.