STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F6UPI5_HORSERRM domain-containing protein. (119 aa)    
Predicted Functional Partners:
RUNX2
Runt-related transcription factor 2; Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. Inhibits KAT6B-dependent transcriptional activation. In osteoblasts, supports transcription activati [...]
   
  0.908
TAF6L
TATA-box binding protein associated factor 6 like.
   
  
 0.844
ZNF35
Zinc finger protein 35.
    
 
 0.843
SFPQ
Splicing factor proline and glutamine rich.
   
 
 0.776
NONO
Non-POU domain containing octamer binding.
   
 
 0.747
PSPC1
Paraspeckle component 1.
   
 
 0.715
TFAP4
Transcription factor AP-4.
      
 0.706
L3MBTL2
L3MBTL histone methyl-lysine binding protein 2.
   
  
 0.702
ILF2
Interleukin enhancer binding factor 2.
   
 
 0.655
C7H19orf53
Chromosome 7 C19orf53 homolog.
   
  
 0.646
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.