STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GSNGelsolin; Calcium-regulated, actin-modulating protein that binds to the plus (or barbed) ends of actin monomers or filaments, preventing monomer exchange (end-blocking or capping). It can promote the assembly of monomers into filaments (nucleation) as well as sever filaments already formed. Plays a role in ciliogenesis (By similarity). (871 aa)    
Predicted Functional Partners:
PIP5K1B
Phosphatidylinositol-4-phosphate 5-kinase type 1 beta.
     
 0.903
SCIN
Scinderin.
  
  
 
0.901
PIKFYVE
Phosphoinositide kinase, FYVE-type zinc finger containing.
     
 0.900
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
     
  0.900
PIP5K1A
PIPK domain-containing protein.
     
  0.900
PIP4K2C
Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma.
     
  0.900
PIP5K1C
Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma.
     
  0.900
PIP4K2A
Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha.
   
 
  0.900
HCLS1
Hematopoietic cell-specific Lyn substrate 1.
   
 0.791
CASP3
Caspase-3-like protein; Belongs to the peptidase C14A family.
    
 0.789
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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