STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DIO1Iodothyronine deiodinase; Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine). (243 aa)    
Predicted Functional Partners:
AADAT
Aminoadipate aminotransferase.
   
  
 0.495
THRA
Thyroid hormone receptor alpha.
   
  
 0.484
MBIP
MAP3K12 binding inhibitory protein 1.
      
 0.483
SLC17A4
Solute carrier family 17 member 4.
   
  
 0.476
SLC17A2
Solute carrier family 17 member 2.
   
  
 0.476
YME1L1
YME1 like 1 ATPase.
      
 0.474
AFG3L2
AFG3 like matrix AAA peptidase subunit 2.
      
 0.463
LOC100052875
AAA domain-containing protein.
      
 0.463
TTF1
Transcription termination factor 1.
      
 0.461
IYD
Iodotyrosine deiodinase.
   
  
 0.456
Your Current Organism:
Equus caballus
NCBI taxonomy Id: 9796
Other names: E. caballus, Equus przewalskii f. caballus, Equus przewalskii forma caballus, domestic horse, equine, horse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.