STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEP12975.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (915 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 
 0.926
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
     
 0.925
AEP12135.1
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.925
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
   
 
 0.917
AEP12385.1
Pyruvate phosphate dikinase; Belongs to the PEP-utilizing enzyme family.
     
 0.911
AEP12067.1
Glutamate synthase domain 2.
  
  
 0.882
AEP10885.1
Citrate synthase; Belongs to the citrate synthase family.
     
 0.850
AEP11367.1
Putative metal-dependent hydrolase.
     
  0.800
AEP11785.1
N-formylglutamate amidohydrolase.
     
  0.800
AEP11712.1
Multidrug resistance efflux pump.
      
 0.682
Your Current Organism:
Chloracidobacterium thermophilum
NCBI taxonomy Id: 981222
Other names: C. thermophilum B, Candidatus Chloracidobacterium thermophilum B, Chloracidobacterium thermophilum B, Chloracidobacterium thermophilum str. B, Chloracidobacterium thermophilum strain B
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