node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACACA | ACACB | ENSSSCP00000047454 | ENSSSCP00000067823 | Acetyl-CoA carboxylase alpha. | Biotin carboxylation domain-containing protein. | 0.932 |
ACACA | GYS1 | ENSSSCP00000047454 | ENSSSCP00000003419 | Acetyl-CoA carboxylase alpha. | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. | 0.458 |
ACACA | PRKAA1 | ENSSSCP00000047454 | ENSSSCP00000024198 | Acetyl-CoA carboxylase alpha. | Non-specific serine/threonine protein kinase. | 0.943 |
ACACA | PRKAA2 | ENSSSCP00000047454 | ENSSSCP00000055569 | Acetyl-CoA carboxylase alpha. | 5'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] | 0.954 |
ACACA | PRKAB1 | ENSSSCP00000047454 | ENSSSCP00000010503 | Acetyl-CoA carboxylase alpha. | 5'-AMP-activated protein kinase subunit beta-1; Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a reg [...] | 0.953 |
ACACA | PRKAB2 | ENSSSCP00000047454 | ENSSSCP00000007147 | Acetyl-CoA carboxylase alpha. | Protein kinase AMP-activated non-catalytic subunit beta 2. | 0.914 |
ACACA | PRKAG1 | ENSSSCP00000047454 | ENSSSCP00000000193 | Acetyl-CoA carboxylase alpha. | 5'-AMP-activated protein kinase subunit gamma-1; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] | 0.926 |
ACACA | PRKAG3 | ENSSSCP00000047454 | ENSSSCP00000017163 | Acetyl-CoA carboxylase alpha. | 5'-AMP-activated protein kinase subunit gamma-3; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] | 0.908 |
ACACB | ACACA | ENSSSCP00000067823 | ENSSSCP00000047454 | Biotin carboxylation domain-containing protein. | Acetyl-CoA carboxylase alpha. | 0.932 |
ACACB | GYS1 | ENSSSCP00000067823 | ENSSSCP00000003419 | Biotin carboxylation domain-containing protein. | Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. | 0.402 |
ACACB | PRKAA1 | ENSSSCP00000067823 | ENSSSCP00000024198 | Biotin carboxylation domain-containing protein. | Non-specific serine/threonine protein kinase. | 0.935 |
ACACB | PRKAA2 | ENSSSCP00000067823 | ENSSSCP00000055569 | Biotin carboxylation domain-containing protein. | 5'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] | 0.949 |
ACACB | PRKAB1 | ENSSSCP00000067823 | ENSSSCP00000010503 | Biotin carboxylation domain-containing protein. | 5'-AMP-activated protein kinase subunit beta-1; Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a reg [...] | 0.950 |
ACACB | PRKAB2 | ENSSSCP00000067823 | ENSSSCP00000007147 | Biotin carboxylation domain-containing protein. | Protein kinase AMP-activated non-catalytic subunit beta 2. | 0.932 |
ACACB | PRKAG1 | ENSSSCP00000067823 | ENSSSCP00000000193 | Biotin carboxylation domain-containing protein. | 5'-AMP-activated protein kinase subunit gamma-1; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] | 0.927 |
ACACB | PRKAG3 | ENSSSCP00000067823 | ENSSSCP00000017163 | Biotin carboxylation domain-containing protein. | 5'-AMP-activated protein kinase subunit gamma-3; AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a [...] | 0.911 |
CAMKK2 | PRKAA1 | ENSSSCP00000010478 | ENSSSCP00000024198 | Calcium/calmodulin-dependent protein kinase kinase 2 isoform 1. | Non-specific serine/threonine protein kinase. | 0.932 |
CAMKK2 | PRKAA2 | ENSSSCP00000010478 | ENSSSCP00000055569 | Calcium/calmodulin-dependent protein kinase kinase 2 isoform 1. | 5'-AMP-activated protein kinase catalytic subunit alpha-2; Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts a [...] | 0.932 |
CAMKK2 | PRKAB1 | ENSSSCP00000010478 | ENSSSCP00000010503 | Calcium/calmodulin-dependent protein kinase kinase 2 isoform 1. | 5'-AMP-activated protein kinase subunit beta-1; Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a reg [...] | 0.942 |
CAMKK2 | PRKAB2 | ENSSSCP00000010478 | ENSSSCP00000007147 | Calcium/calmodulin-dependent protein kinase kinase 2 isoform 1. | Protein kinase AMP-activated non-catalytic subunit beta 2. | 0.942 |