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DDX39B protein (Sus scrofa) - STRING interaction network
"DDX39B" - Spliceosome RNA helicase DDX39B in Sus scrofa
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
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[Homology]
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DDX39BSpliceosome RNA helicase DDX39B; Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription- independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5’ end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pa [...] (428 aa)    
Predicted Functional Partners:
CHTOP
PC1orf77; Sus scrofa chromatin target of PRMT1 (CHTOP), mRNA (249 aa)
     
  0.996
THOC2
THO complex 2 (1601 aa)
     
  0.994
SARNP
SAP domain containing ribonucleoprotein (210 aa)
     
  0.994
THOC3
THO complex 3 (351 aa)
     
  0.993
THOC1
THO complex 1 (662 aa)
     
  0.992
POLDIP3
Polymerase (DNA-directed), delta interacting protein 3 (338 aa)
     
  0.992
THOC7
THO complex 7 homolog (Drosophila) (204 aa)
     
  0.991
RBM8A
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs (177 aa)
     
  0.990
THOC6
Uncharacterized protein; THO complex 6 homolog (Drosophila) (341 aa)
 
 
  0.990
SRSF1
Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5’- and 3’-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5’-splice site-containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5’-RGAAGAAC-3’ (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5’- CGAGGCG-3’ motif in vitro. Three copies of the octame [...] (248 aa)
   
  0.989
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, Sus scrofa, pig, pigs, swine, wild boar
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