STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (471 aa)    
Predicted Functional Partners:
EIF4E
Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.
    
 0.957
MAPK3
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.946
MAPK1
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
   
0.946
EIF4E1B
Eukaryotic translation initiation factor 4E family member 1B; Belongs to the eukaryotic initiation factor 4E family.
    
 0.929
MKNK2
MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily.
  
  
0.903
EIF4E2
Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family.
     
  0.900
DCX
Doublecortin.
 
      0.660
LURAP1
Leucine rich adaptor protein 1.
      
 0.654
TTC39C
Tetratricopeptide repeat protein 39C isoform 1.
      
 0.588
TP53INP1
Tumor protein p53-inducible nuclear protein 1 isoform X1.
   
  
 0.588
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.