STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHACTR2Phosphatase and actin regulator. (759 aa)    
Predicted Functional Partners:
TMEM150C
Transmembrane protein 150C.
      
 0.900
GPRC5C
G protein-coupled receptor class C group 5 member C.
      
 0.897
CACNA1I
Voltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...]
      
 0.653
ARFGEF3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3 isoform X1.
      
 0.576
NEXMIF
Neurite extension and migration factor.
      
 0.570
SERPINI2
Serpin family I member 2; Belongs to the serpin family.
      
 0.561
GRHPR
Glyoxylate and hydroxypyruvate reductase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
      
 0.546
RASGEF1B
RasGEF domain family member 1B.
   
  
 0.527
PPP1CA
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 
 0.522
PPP1CC
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 
 0.522
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.