CRNN protein (Sus scrofa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
some 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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[Homology]

Score

CRNN

Uncharacterized protein; Cornulin (603 aa)

Predicted Functional Partners:

BLOC1S1

0.827

KPRP

0.714

C10orf10

0.683

KRT78

0.588

SAMD14

0.576

ADAMTS20

0.574

GOT2

0.561

GOT1

0.561

CASP14

0.560

PMEL

0.531

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAMTS20	BLOC1S1	ENSSSCP00000000845	ENSSSCP00000000375	Uncharacterized protein; ADAM metallopeptidase with thrombospondin type 1 motif, 20	Biogenesis of lysosomal organelles complex 1 subunit 1	0.704
ADAMTS20	CRNN	ENSSSCP00000000845	ENSSSCP00000007042	Uncharacterized protein; ADAM metallopeptidase with thrombospondin type 1 motif, 20	Uncharacterized protein; Cornulin	0.574
ADAMTS20	KPRP	ENSSSCP00000000845	ENSSSCP00000019297	Uncharacterized protein; ADAM metallopeptidase with thrombospondin type 1 motif, 20	Keratinocyte proline-rich protein	0.438
BLOC1S1	ADAMTS20	ENSSSCP00000000375	ENSSSCP00000000845	Biogenesis of lysosomal organelles complex 1 subunit 1	Uncharacterized protein; ADAM metallopeptidase with thrombospondin type 1 motif, 20	0.704
BLOC1S1	CRNN	ENSSSCP00000000375	ENSSSCP00000007042	Biogenesis of lysosomal organelles complex 1 subunit 1	Uncharacterized protein; Cornulin	0.827
BLOC1S1	KPRP	ENSSSCP00000000375	ENSSSCP00000019297	Biogenesis of lysosomal organelles complex 1 subunit 1	Keratinocyte proline-rich protein	0.761
BLOC1S1	PMEL	ENSSSCP00000000375	ENSSSCP00000000388	Biogenesis of lysosomal organelles complex 1 subunit 1	Melanocyte protein pmel; Premelanosome protein	0.673
BLOC1S1	SAMD14	ENSSSCP00000000375	ENSSSCP00000018638	Biogenesis of lysosomal organelles complex 1 subunit 1	Sterile alpha motif domain containing 14	0.700
C10orf10	CRNN	ENSSSCP00000027008	ENSSSCP00000007042	Chromosome 10 open reading frame 10	Uncharacterized protein; Cornulin	0.683
CASP14	CRNN	ENSSSCP00000014708	ENSSSCP00000007042	Caspase 14, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family	Uncharacterized protein; Cornulin	0.560
CRNN	ADAMTS20	ENSSSCP00000007042	ENSSSCP00000000845	Uncharacterized protein; Cornulin	Uncharacterized protein; ADAM metallopeptidase with thrombospondin type 1 motif, 20	0.574
CRNN	BLOC1S1	ENSSSCP00000007042	ENSSSCP00000000375	Uncharacterized protein; Cornulin	Biogenesis of lysosomal organelles complex 1 subunit 1	0.827
CRNN	C10orf10	ENSSSCP00000007042	ENSSSCP00000027008	Uncharacterized protein; Cornulin	Chromosome 10 open reading frame 10	0.683
CRNN	CASP14	ENSSSCP00000007042	ENSSSCP00000014708	Uncharacterized protein; Cornulin	Caspase 14, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family	0.560
CRNN	GOT1	ENSSSCP00000007042	ENSSSCP00000011226	Uncharacterized protein; Cornulin	Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate or L- cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H(2)S via the action of 3- [...]	0.561
CRNN	GOT2	ENSSSCP00000007042	ENSSSCP00000003017	Uncharacterized protein; Cornulin	Aspartate aminotransferase, mitochondrial precursor; Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids (By similarity)	0.561
CRNN	KPRP	ENSSSCP00000007042	ENSSSCP00000019297	Uncharacterized protein; Cornulin	Keratinocyte proline-rich protein	0.714
CRNN	KRT78	ENSSSCP00000007042	ENSSSCP00000000264	Uncharacterized protein; Cornulin	Keratin, type ii cytoskeletal 71; Belongs to the intermediate filament family	0.588
CRNN	PMEL	ENSSSCP00000007042	ENSSSCP00000000388	Uncharacterized protein; Cornulin	Melanocyte protein pmel; Premelanosome protein	0.531
CRNN	SAMD14	ENSSSCP00000007042	ENSSSCP00000018638	Uncharacterized protein; Cornulin	Sterile alpha motif domain containing 14	0.576