node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGT | ENPEP | ENSSSCP00000029872 | ENSSSCP00000064005 | Angiotensinogen; Belongs to the serpin family. | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | 0.889 |
DNPEP | ENPEP | ENSSSCP00000044799 | ENSSSCP00000064005 | Aspartyl aminopeptidase. | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | 0.673 |
DNPEP | XPNPEP3 | ENSSSCP00000044799 | ENSSSCP00000033364 | Aspartyl aminopeptidase. | Putative Xaa-Pro aminopeptidase 3 isoform X1. | 0.659 |
DPP4 | ENPEP | ENSSSCP00000059750 | ENSSSCP00000064005 | Dipeptidyl peptidase 4 membrane form; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the mi [...] | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | 0.827 |
DPP4 | MGAM2 | ENSSSCP00000059750 | ENSSSCP00000038364 | Dipeptidyl peptidase 4 membrane form; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the mi [...] | Maltase-glucoamylase 2 (putative). | 0.472 |
DPP4 | SI | ENSSSCP00000059750 | ENSSSCP00000023767 | Dipeptidyl peptidase 4 membrane form; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the mi [...] | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides (By similarity). | 0.694 |
ENPEP | AGT | ENSSSCP00000064005 | ENSSSCP00000029872 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | Angiotensinogen; Belongs to the serpin family. | 0.889 |
ENPEP | DNPEP | ENSSSCP00000064005 | ENSSSCP00000044799 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | Aspartyl aminopeptidase. | 0.673 |
ENPEP | DPP4 | ENSSSCP00000064005 | ENSSSCP00000059750 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | Dipeptidyl peptidase 4 membrane form; Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T- cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the mi [...] | 0.827 |
ENPEP | ERBB3 | ENSSSCP00000064005 | ENSSSCP00000019799 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | Erb-b2 receptor tyrosine kinase 3. | 0.655 |
ENPEP | MAP2K5 | ENSSSCP00000064005 | ENSSSCP00000067190 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | Mitogen-activated protein kinase kinase 5. | 0.722 |
ENPEP | MGAM | ENSSSCP00000064005 | ENSSSCP00000037102 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | Maltase-glucoamylase, intestinal. | 0.672 |
ENPEP | MGAM2 | ENSSSCP00000064005 | ENSSSCP00000038364 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | Maltase-glucoamylase 2 (putative). | 0.777 |
ENPEP | SI | ENSSSCP00000064005 | ENSSSCP00000023767 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | Sucrase-isomaltase, intestinal; Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides (By similarity). | 0.834 |
ENPEP | XPNPEP1 | ENSSSCP00000064005 | ENSSSCP00000031394 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | X-prolyl aminopeptidase 1; Belongs to the peptidase M24B family. | 0.660 |
ENPEP | XPNPEP3 | ENSSSCP00000064005 | ENSSSCP00000033364 | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | Putative Xaa-Pro aminopeptidase 3 isoform X1. | 0.647 |
ERBB3 | ENPEP | ENSSSCP00000019799 | ENSSSCP00000064005 | Erb-b2 receptor tyrosine kinase 3. | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | 0.655 |
MAP2K5 | ENPEP | ENSSSCP00000067190 | ENSSSCP00000064005 | Mitogen-activated protein kinase kinase 5. | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | 0.722 |
MGAM | ENPEP | ENSSSCP00000037102 | ENSSSCP00000064005 | Maltase-glucoamylase, intestinal. | Glutamyl aminopeptidase; Regulates central hypertension through its calcium-modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II; Belongs to the peptidase M1 family. | 0.672 |
MGAM | MGAM2 | ENSSSCP00000037102 | ENSSSCP00000038364 | Maltase-glucoamylase, intestinal. | Maltase-glucoamylase 2 (putative). | 0.902 |