STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDNRBEndothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (443 aa)    
Predicted Functional Partners:
EDN1
Endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides
    
 0.998
EDN3
Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides
   
 0.991
AGT
Angiotensinogen (serpin peptidase inhibitor, clade A, member 8); Belongs to the serpin family
   
 0.943
KNG1
Kininogen 1
    
 0.935
AVPR1B
Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system
     
 0.935
AVP
Vasopressin-neurophysin 2-copeptin; Neurophysin 2 specifically binds vasopressin
    
 0.930
NTS
Neurotensin
   
 0.929
ADRA1B
Adrenoceptor alpha 1B
   
 
0.928
GPR143
G protein-coupled receptor 143
   
 
 0.927
AVPR1A
Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system
     
0.924
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, Sus scrofa, pig, pigs, swine, wild boar
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