TSC22D3 protein (Sus scrofa) - STRING interaction network

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TSC22D3

TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...] (267 aa)

Predicted Functional Partners:

ZNF35

0.733

FKBP5

0.717

TAF6L

0.680

NRBP1

0.629

TMEM47

0.613

TFAP4

0.587

CXXC1

0.572

TCFL5

0.572

SGK1

0.563

TSC22D2

0.556

Your Current Organism:

Sus scrofa

NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CXXC1	TAF6L	ENSSSCP00000043581	ENSSSCP00000026008	CXXC finger protein 1.	TATA-box binding protein associated factor 6 like.	0.762
CXXC1	TFAP4	ENSSSCP00000043581	ENSSSCP00000043207	CXXC finger protein 1.	Transcription factor AP-4.	0.654
CXXC1	TSC22D3	ENSSSCP00000043581	ENSSSCP00000062162	CXXC finger protein 1.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.572
CXXC1	ZNF35	ENSSSCP00000043581	ENSSSCP00000042963	CXXC finger protein 1.	Zinc finger protein 35.	0.799
FKBP5	SGK1	ENSSSCP00000033815	ENSSSCP00000039609	Peptidylprolyl isomerase.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.607
FKBP5	TSC22D3	ENSSSCP00000033815	ENSSSCP00000062162	Peptidylprolyl isomerase.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.717
NRBP1	TSC22D2	ENSSSCP00000020910	ENSSSCP00000012480	Nuclear receptor binding protein 1.	TSC22 domain family protein 2 isoform 1.	0.781
NRBP1	TSC22D3	ENSSSCP00000020910	ENSSSCP00000062162	Nuclear receptor binding protein 1.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.629
SGK1	FKBP5	ENSSSCP00000039609	ENSSSCP00000033815	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Peptidylprolyl isomerase.	0.607
SGK1	TSC22D3	ENSSSCP00000039609	ENSSSCP00000062162	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.563
TAF6L	CXXC1	ENSSSCP00000026008	ENSSSCP00000043581	TATA-box binding protein associated factor 6 like.	CXXC finger protein 1.	0.762
TAF6L	TFAP4	ENSSSCP00000026008	ENSSSCP00000043207	TATA-box binding protein associated factor 6 like.	Transcription factor AP-4.	0.875
TAF6L	TSC22D3	ENSSSCP00000026008	ENSSSCP00000062162	TATA-box binding protein associated factor 6 like.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.680
TAF6L	ZNF35	ENSSSCP00000026008	ENSSSCP00000042963	TATA-box binding protein associated factor 6 like.	Zinc finger protein 35.	0.908
TCFL5	TSC22D3	ENSSSCP00000064334	ENSSSCP00000062162	Transcription factor like 5.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.572
TFAP4	CXXC1	ENSSSCP00000043207	ENSSSCP00000043581	Transcription factor AP-4.	CXXC finger protein 1.	0.654
TFAP4	TAF6L	ENSSSCP00000043207	ENSSSCP00000026008	Transcription factor AP-4.	TATA-box binding protein associated factor 6 like.	0.875
TFAP4	TSC22D3	ENSSSCP00000043207	ENSSSCP00000062162	Transcription factor AP-4.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.587
TFAP4	ZNF35	ENSSSCP00000043207	ENSSSCP00000042963	Transcription factor AP-4.	Zinc finger protein 35.	0.880
TMEM47	TSC22D3	ENSSSCP00000024570	ENSSSCP00000062162	Transmembrane protein 47.	TSC22 domain family protein 3; Protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Inhibits myogenic differentiation and mediates anti-myogenic effects of glucocorticoids by binding and regulating MYOD1 and HDAC1 transcr [...]	0.613

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