STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAN2B2Epididymis-specific alpha-mannosidase; Can digest both p-nitro-phenyl-alpha-D-mannoside and high mannose oligosaccharide (Man(8)-GlcNAc(2)). May be involved in sperm maturation. Has a possible role in specific sperm-egg interaction since sperm surface mannosidase acts like a receptor for mannose-containing oligosaccharides located on the zona pellucida. (1039 aa)    
Predicted Functional Partners:
MAN2C1
Mannosidase alpha class 2C member 1.
     
 0.930
MAN2B1
Alpha-mannosidase.
  
  
0.911
LRPAP1
Alpha-2-macroglobulin receptor-associated protein.
      
 0.569
PDE6B
Phosphodiesterase.
      
 0.549
PPP2R2C
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
      
 0.545
LOC100737744
Olfactory receptor.
      
 0.534
PCGF3
Polycomb group ring finger 3.
      
 0.522
MANBA
Mannosidase beta.
   
 
 0.510
PLCL2
Phosphoinositide phospholipase C.
      
 0.508
FGFBP1
Fibroblast growth factor-binding protein 1.
      
 0.500
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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