node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATAT1 | COMMD6 | ENSSSCP00000020536 | ENSSSCP00000064850 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | Uncharacterized protein. | 0.548 |
ATAT1 | HDAC6 | ENSSSCP00000020536 | ENSSSCP00000058228 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | Histone deacetylase 6. | 0.862 |
ATAT1 | MSH5 | ENSSSCP00000020536 | ENSSSCP00000034231 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.792 |
ATAT1 | NANOS3 | ENSSSCP00000020536 | ENSSSCP00000014628 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | Nanos C2HC-type zinc finger 3; Belongs to the nanos family. | 0.555 |
ATAT1 | NEDD1 | ENSSSCP00000020536 | ENSSSCP00000058867 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | NEDD1 gamma-tubulin ring complex targeting factor. | 0.612 |
ATAT1 | NEK9 | ENSSSCP00000020536 | ENSSSCP00000068861 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | NIMA related kinase 9. | 0.531 |
ATAT1 | SIRT2 | ENSSSCP00000020536 | ENSSSCP00000064320 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.775 |
ATAT1 | SPAST | ENSSSCP00000020536 | ENSSSCP00000068761 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Severing activity is not dependent on tubulin acetylation or detyrosination. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation [...] | 0.590 |
ATAT1 | SYCE2 | ENSSSCP00000020536 | ENSSSCP00000014609 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | Synaptonemal complex central element protein 2. | 0.724 |
ATAT1 | TDRD5 | ENSSSCP00000020536 | ENSSSCP00000016462 | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | Tudor domain containing 5. | 0.547 |
COMMD6 | ATAT1 | ENSSSCP00000064850 | ENSSSCP00000020536 | Uncharacterized protein. | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | 0.548 |
COMMD6 | MSH5 | ENSSSCP00000064850 | ENSSSCP00000034231 | Uncharacterized protein. | DNA_MISMATCH_REPAIR_2 domain-containing protein. | 0.762 |
COMMD6 | NANOS3 | ENSSSCP00000064850 | ENSSSCP00000014628 | Uncharacterized protein. | Nanos C2HC-type zinc finger 3; Belongs to the nanos family. | 0.478 |
COMMD6 | SYCE2 | ENSSSCP00000064850 | ENSSSCP00000014609 | Uncharacterized protein. | Synaptonemal complex central element protein 2. | 0.547 |
COMMD6 | TDRD5 | ENSSSCP00000064850 | ENSSSCP00000016462 | Uncharacterized protein. | Tudor domain containing 5. | 0.512 |
HDAC6 | ATAT1 | ENSSSCP00000058228 | ENSSSCP00000020536 | Histone deacetylase 6. | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | 0.862 |
HDAC6 | SIRT2 | ENSSSCP00000058228 | ENSSSCP00000064320 | Histone deacetylase 6. | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. | 0.783 |
MSH5 | ATAT1 | ENSSSCP00000034231 | ENSSSCP00000020536 | DNA_MISMATCH_REPAIR_2 domain-containing protein. | Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] | 0.792 |
MSH5 | COMMD6 | ENSSSCP00000034231 | ENSSSCP00000064850 | DNA_MISMATCH_REPAIR_2 domain-containing protein. | Uncharacterized protein. | 0.762 |
MSH5 | NANOS3 | ENSSSCP00000034231 | ENSSSCP00000014628 | DNA_MISMATCH_REPAIR_2 domain-containing protein. | Nanos C2HC-type zinc finger 3; Belongs to the nanos family. | 0.617 |