STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAP1GAPRAP1 GTPase activating protein. (754 aa)    
Predicted Functional Partners:
RAP1B
RAP1B, member of RAS oncogene family.
    
 0.981
RAP1A
RAP1A, member of RAS oncogene family.
    
 0.956
RALGDS
Uncharacterized protein.
   
  
 0.602
RALB
RAS like proto-oncogene B.
    
 
 0.593
GFRA2
GDNF family receptor alpha-2; Receptor for neurturin. Mediates the NRTN-induced autophosphorylation and activation of the RET receptor. Also able to mediate GDNF signaling through the RET tyrosine kinase receptor.
   
 
 0.533
APBB1IP
Amyloid beta precursor protein binding family B member 1 interacting protein.
   
  
 0.523
GFRA1
GDNF family receptor alpha 1.
   
 
  0.522
GPSM1
G protein signaling modulator 1.
      
 0.522
RAP1GDS1
Rap1 GTPase-GDP dissociation stimulator 1.
      
 0.509
RET
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
     
  0.499
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, pig, pigs, swine, wild boar
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.