node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SGRA_1194 | mqnA | SGRA_1194 | SGRA_3723 | Amidohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.719 |
SGRA_1194 | mqnC | SGRA_1194 | SGRA_1344 | Amidohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.683 |
SGRA_1194 | mqnD | SGRA_1194 | SGRA_0777 | Amidohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.594 |
SGRA_1194 | mqnE | SGRA_1194 | SGRA_3725 | Amidohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.969 |
SGRA_1194 | mtnN | SGRA_1194 | SGRA_1216 | Amidohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | Purine or other phosphorylase family 1; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.961 |
SGRA_1194 | ubiA | SGRA_1194 | SGRA_1441 | Amidohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family. | 0.586 |
glcD | ubiA | SGRA_3318 | SGRA_1441 | (S)-2-hydroxy-acid oxidase; COG0277 FAD/FMN-containing dehydrogenases. | COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family. | 0.469 |
ispB | ubiA | SGRA_3754 | SGRA_1441 | Polyprenyl synthetase; COG0142 Geranylgeranyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. | COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family. | 0.849 |
mqnA | SGRA_1194 | SGRA_3723 | SGRA_1194 | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Amidohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.719 |
mqnA | mqnC | SGRA_3723 | SGRA_1344 | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.941 |
mqnA | mqnD | SGRA_3723 | SGRA_0777 | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.846 |
mqnA | mqnE | SGRA_3723 | SGRA_3725 | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Radical SAM domain protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.996 |
mqnA | mtnN | SGRA_3723 | SGRA_1216 | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Purine or other phosphorylase family 1; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.786 |
mqnA | ubiA | SGRA_3723 | SGRA_1441 | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases; Belongs to the UbiA prenyltransferase family. | 0.797 |
mqnA | ubiD | SGRA_3723 | SGRA_1771 | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | UbiD family decarboxylase; COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; Belongs to the UbiD family. | 0.747 |
mqnA | ubiX | SGRA_3723 | SGRA_1042 | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.589 |
mqnC | SGRA_1194 | SGRA_1344 | SGRA_1194 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Amidohydrolase; COG0402 Cytosine deaminase and related metal-dependent hydrolases. | 0.683 |
mqnC | mqnA | SGRA_1344 | SGRA_3723 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.941 |
mqnC | mqnD | SGRA_1344 | SGRA_0777 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.979 |
mqnC | mtnN | SGRA_1344 | SGRA_1216 | Radical SAM domain protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | Purine or other phosphorylase family 1; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.969 |