node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AET59376.1 | AET59575.1 | HPL003_13115 | HPL003_14120 | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.937 |
AET59376.1 | AET61184.1 | HPL003_13115 | HPL003_22290 | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetyl-coenzyme A synthetase (acetate--CoA ligase); COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.920 |
AET59376.1 | AET61456.1 | HPL003_13115 | HPL003_23690 | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 0.942 |
AET59376.1 | AET61457.1 | HPL003_13115 | HPL003_23695 | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. | 0.924 |
AET59376.1 | AET61537.1 | HPL003_13115 | HPL003_24095 | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.942 |
AET59376.1 | AET61564.1 | HPL003_13115 | HPL003_24230 | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.925 |
AET59376.1 | iolA | HPL003_13115 | HPL003_12850 | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. | 0.825 |
AET59376.1 | leuA | HPL003_13115 | HPL003_15495 | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.917 |
AET59575.1 | AET59376.1 | HPL003_14120 | HPL003_13115 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG0119 Isopropylmalate/homocitrate/citramalate synthases; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.937 |
AET59575.1 | AET59991.1 | HPL003_14120 | HPL003_16225 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 2-methylcitrate synthase/citrate synthase ii; COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.957 |
AET59575.1 | AET61184.1 | HPL003_14120 | HPL003_22290 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Acetyl-coenzyme A synthetase (acetate--CoA ligase); COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.962 |
AET59575.1 | AET61456.1 | HPL003_14120 | HPL003_23690 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 0.942 |
AET59575.1 | AET61457.1 | HPL003_14120 | HPL003_23695 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | COG1014 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit. | 0.941 |
AET59575.1 | AET61537.1 | HPL003_14120 | HPL003_24095 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.937 |
AET59575.1 | AET61564.1 | HPL003_14120 | HPL003_24230 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; COG1012 NAD-dependent aldehyde dehydrogenases; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.946 |
AET59575.1 | iolA | HPL003_14120 | HPL003_12850 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. | 0.919 |
AET59575.1 | leuA | HPL003_14120 | HPL003_15495 | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.937 |
AET59991.1 | AET59575.1 | HPL003_16225 | HPL003_14120 | 2-methylcitrate synthase/citrate synthase ii; COG0372 Citrate synthase; Belongs to the citrate synthase family. | COG0183 Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.957 |
AET59991.1 | AET61184.1 | HPL003_16225 | HPL003_22290 | 2-methylcitrate synthase/citrate synthase ii; COG0372 Citrate synthase; Belongs to the citrate synthase family. | Acetyl-coenzyme A synthetase (acetate--CoA ligase); COG0365 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases. | 0.974 |
AET59991.1 | AET61456.1 | HPL003_16225 | HPL003_23690 | 2-methylcitrate synthase/citrate synthase ii; COG0372 Citrate synthase; Belongs to the citrate synthase family. | COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit. | 0.947 |