node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYP4F2 | GGCX | ENSBTAP00000058368 | ENSBTAP00000027811 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | 0.460 |
CYP4F2 | VKORC1 | ENSBTAP00000058368 | ENSBTAP00000000519 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Vitamin K epoxide reductase complex subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development (By similarity). | 0.678 |
CYP4F2-2 | GGCX | ENSBTAP00000072588 | ENSBTAP00000027811 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | 0.413 |
CYP4F2-2 | VKORC1 | ENSBTAP00000072588 | ENSBTAP00000000519 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Vitamin K epoxide reductase complex subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development (By similarity). | 0.671 |
DCLRE1A | PLCD3 | ENSBTAP00000026896 | ENSBTAP00000034705 | DNA cross-link repair 1A. | Phosphoinositide phospholipase C. | 0.554 |
DCLRE1A | VKORC1 | ENSBTAP00000026896 | ENSBTAP00000000519 | DNA cross-link repair 1A. | Vitamin K epoxide reductase complex subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development (By similarity). | 0.575 |
GGCX | CYP4F2 | ENSBTAP00000027811 | ENSBTAP00000058368 | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.460 |
GGCX | CYP4F2-2 | ENSBTAP00000027811 | ENSBTAP00000072588 | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.413 |
GGCX | NQO1 | ENSBTAP00000027811 | ENSBTAP00000071181 | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | NAD(P)H quinone dehydrogenase 1. | 0.927 |
GGCX | PROS1 | ENSBTAP00000027811 | ENSBTAP00000069933 | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. | 0.962 |
GGCX | VKORC1 | ENSBTAP00000027811 | ENSBTAP00000000519 | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | Vitamin K epoxide reductase complex subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development (By similarity). | 0.986 |
GGCX | VKORC1L1 | ENSBTAP00000027811 | ENSBTAP00000055029 | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | Vitamin K epoxide reductase complex subunit 1 like 1. | 0.932 |
NQO1 | GGCX | ENSBTAP00000071181 | ENSBTAP00000027811 | NAD(P)H quinone dehydrogenase 1. | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | 0.927 |
NQO1 | VKORC1 | ENSBTAP00000071181 | ENSBTAP00000000519 | NAD(P)H quinone dehydrogenase 1. | Vitamin K epoxide reductase complex subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development (By similarity). | 0.924 |
NQO1 | VKORC1L1 | ENSBTAP00000071181 | ENSBTAP00000055029 | NAD(P)H quinone dehydrogenase 1. | Vitamin K epoxide reductase complex subunit 1 like 1. | 0.914 |
PLCD3 | DCLRE1A | ENSBTAP00000034705 | ENSBTAP00000026896 | Phosphoinositide phospholipase C. | DNA cross-link repair 1A. | 0.554 |
PLCD3 | VKORC1 | ENSBTAP00000034705 | ENSBTAP00000000519 | Phosphoinositide phospholipase C. | Vitamin K epoxide reductase complex subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development (By similarity). | 0.590 |
PROS1 | GGCX | ENSBTAP00000069933 | ENSBTAP00000027811 | Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. | Vitamin K-dependent gamma-carboxylase; Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide. | 0.962 |
PROS1 | VKORC1 | ENSBTAP00000069933 | ENSBTAP00000000519 | Vitamin K-dependent protein S; Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis. | Vitamin K epoxide reductase complex subunit 1; Involved in vitamin K metabolism. Catalytic subunit of the vitamin K epoxide reductase (VKOR) complex which reduces inactive vitamin K 2,3-epoxide to active vitamin K. Vitamin K is required for the gamma-carboxylation of various proteins, including clotting factors, and is required for normal blood coagulation, but also for normal bone development (By similarity). | 0.620 |
THYN1 | TRPT1 | ENSBTAP00000060387 | ENSBTAP00000022022 | Thymocyte nuclear protein 1. | tRNA 2'-phosphotransferase 1; Catalyzes the last step of tRNA splicing, the transfer of the splice junction 2'-phosphate from ligated tRNA to NAD to produce ADP- ribose 1''-2'' cyclic phosphate; Belongs to the KptA/TPT1 family. | 0.805 |