node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CELA3B | CPB1 | ENSBTAP00000017401 | ENSBTAP00000000580 | Proproteinase E; May protect procarboxypeptidase A against denaturation in the acidic environment of the ruminant duodenum; Belongs to the peptidase S1 family. | Carboxypeptidase B; Belongs to the peptidase M14 family. | 0.743 |
CELA3B | CTRB1 | ENSBTAP00000017401 | ENSBTAP00000011204 | Proproteinase E; May protect procarboxypeptidase A against denaturation in the acidic environment of the ruminant duodenum; Belongs to the peptidase S1 family. | Chymotrypsin B chain A; Belongs to the peptidase S1 family. | 0.764 |
CELA3B | LOC100848132 | ENSBTAP00000017401 | ENSBTAP00000065010 | Proproteinase E; May protect procarboxypeptidase A against denaturation in the acidic environment of the ruminant duodenum; Belongs to the peptidase S1 family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.792 |
CELA3B | LOC618826 | ENSBTAP00000017401 | ENSBTAP00000050246 | Proproteinase E; May protect procarboxypeptidase A against denaturation in the acidic environment of the ruminant duodenum; Belongs to the peptidase S1 family. | CTRB1 protein; Belongs to the peptidase S1 family. | 0.767 |
CPB1 | CELA3B | ENSBTAP00000000580 | ENSBTAP00000017401 | Carboxypeptidase B; Belongs to the peptidase M14 family. | Proproteinase E; May protect procarboxypeptidase A against denaturation in the acidic environment of the ruminant duodenum; Belongs to the peptidase S1 family. | 0.743 |
CPB1 | CPB2 | ENSBTAP00000000580 | ENSBTAP00000009300 | Carboxypeptidase B; Belongs to the peptidase M14 family. | Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. | 0.916 |
CPB1 | CPE | ENSBTAP00000000580 | ENSBTAP00000021955 | Carboxypeptidase B; Belongs to the peptidase M14 family. | Carboxypeptidase E; Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage. | 0.875 |
CPB1 | CTRB1 | ENSBTAP00000000580 | ENSBTAP00000011204 | Carboxypeptidase B; Belongs to the peptidase M14 family. | Chymotrypsin B chain A; Belongs to the peptidase S1 family. | 0.791 |
CPB1 | ENSBTAP00000058788 | ENSBTAP00000000580 | ENSBTAP00000058788 | Carboxypeptidase B; Belongs to the peptidase M14 family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.672 |
CPB1 | EPC2 | ENSBTAP00000000580 | ENSBTAP00000024730 | Carboxypeptidase B; Belongs to the peptidase M14 family. | Enhancer of polycomb homolog. | 0.666 |
CPB1 | LOC100848132 | ENSBTAP00000000580 | ENSBTAP00000065010 | Carboxypeptidase B; Belongs to the peptidase M14 family. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.777 |
CPB1 | LOC618826 | ENSBTAP00000000580 | ENSBTAP00000050246 | Carboxypeptidase B; Belongs to the peptidase M14 family. | CTRB1 protein; Belongs to the peptidase S1 family. | 0.790 |
CPB1 | OVCH1 | ENSBTAP00000000580 | ENSBTAP00000007060 | Carboxypeptidase B; Belongs to the peptidase M14 family. | Ovochymase 1; Belongs to the peptidase S1 family. | 0.714 |
CPB1 | PLG | ENSBTAP00000000580 | ENSBTAP00000001674 | Carboxypeptidase B; Belongs to the peptidase M14 family. | Plasmin heavy chain A, short form; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invas [...] | 0.742 |
CPB2 | CPB1 | ENSBTAP00000009300 | ENSBTAP00000000580 | Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. | Carboxypeptidase B; Belongs to the peptidase M14 family. | 0.916 |
CPB2 | CPE | ENSBTAP00000009300 | ENSBTAP00000021955 | Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. | Carboxypeptidase E; Sorting receptor that directs prohormones to the regulated secretory pathway. Acts also as a prohormone processing enzyme in neuro/endocrine cells, removing dibasic residues from the C-terminal end of peptide hormone precursors after initial endoprotease cleavage. | 0.930 |
CPB2 | CTRB1 | ENSBTAP00000009300 | ENSBTAP00000011204 | Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. | Chymotrypsin B chain A; Belongs to the peptidase S1 family. | 0.422 |
CPB2 | LOC100848132 | ENSBTAP00000009300 | ENSBTAP00000065010 | Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. | Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. | 0.421 |
CPB2 | LOC618826 | ENSBTAP00000009300 | ENSBTAP00000050246 | Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. | CTRB1 protein; Belongs to the peptidase S1 family. | 0.422 |
CPB2 | PLG | ENSBTAP00000009300 | ENSBTAP00000001674 | Carboxypeptidase B2; Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. | Plasmin heavy chain A, short form; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invas [...] | 0.665 |