Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| APPBP2 | COMMD1 | ENSBTAP00000068280 | ENSBTAP00000026470 | Amyloid beta precursor protein binding protein 2. | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | 0.540 |
| APPBP2 | CUL2 | ENSBTAP00000068280 | ENSBTAP00000070862 | Amyloid beta precursor protein binding protein 2. | CUL2 protein; Belongs to the cullin family. | 0.748 |
| APPBP2 | FEM1A | ENSBTAP00000068280 | ENSBTAP00000004519 | Amyloid beta precursor protein binding protein 2. | Protein fem-1 homolog A; Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4 (By similarity); Belongs to the fem-1 family. | 0.812 |
| APPBP2 | FEM1B | ENSBTAP00000068280 | ENSBTAP00000011028 | Amyloid beta precursor protein binding protein 2. | Fem-1 homolog B. | 0.763 |
| APPBP2 | FEM1C | ENSBTAP00000068280 | ENSBTAP00000011464 | Amyloid beta precursor protein binding protein 2. | Protein fem-1 homolog C; Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit; Belongs to the fem-1 family. | 0.689 |
| APPBP2 | KLHDC10 | ENSBTAP00000068280 | ENSBTAP00000000718 | Amyloid beta precursor protein binding protein 2. | Kelch domain-containing protein 10; Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C phosphatase activity on MAP3K5 (By similarity). | 0.794 |
| APPBP2 | KLHDC2 | ENSBTAP00000068280 | ENSBTAP00000006490 | Amyloid beta precursor protein binding protein 2. | Kelch domain-containing protein 2; Represses CREB3-mediated transcription by interfering with CREB3-DNA binding. | 0.837 |
| APPBP2 | KLHDC3 | ENSBTAP00000068280 | ENSBTAP00000016944 | Amyloid beta precursor protein binding protein 2. | Kelch domain-containing protein 3; May be involved in meiotic recombination process. | 0.848 |
| BSDC1 | KLHDC10 | ENSBTAP00000066383 | ENSBTAP00000000718 | BSD domain-containing protein 1. | Kelch domain-containing protein 10; Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C phosphatase activity on MAP3K5 (By similarity). | 0.661 |
| COMMD1 | APPBP2 | ENSBTAP00000026470 | ENSBTAP00000068280 | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | Amyloid beta precursor protein binding protein 2. | 0.540 |
| COMMD1 | CUL2 | ENSBTAP00000026470 | ENSBTAP00000070862 | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | CUL2 protein; Belongs to the cullin family. | 0.959 |
| COMMD1 | FEM1A | ENSBTAP00000026470 | ENSBTAP00000004519 | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | Protein fem-1 homolog A; Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4 (By similarity); Belongs to the fem-1 family. | 0.730 |
| COMMD1 | FEM1B | ENSBTAP00000026470 | ENSBTAP00000011028 | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | Fem-1 homolog B. | 0.518 |
| COMMD1 | FEM1C | ENSBTAP00000026470 | ENSBTAP00000011464 | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | Protein fem-1 homolog C; Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit; Belongs to the fem-1 family. | 0.730 |
| COMMD1 | KLHDC10 | ENSBTAP00000026470 | ENSBTAP00000000718 | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | Kelch domain-containing protein 10; Participates in the oxidative stress-induced cell death through MAP3K5 activation. Inhibits PPP5C phosphatase activity on MAP3K5 (By similarity). | 0.723 |
| COMMD1 | KLHDC2 | ENSBTAP00000026470 | ENSBTAP00000006490 | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | Kelch domain-containing protein 2; Represses CREB3-mediated transcription by interfering with CREB3-DNA binding. | 0.723 |
| COMMD1 | KLHDC3 | ENSBTAP00000026470 | ENSBTAP00000016944 | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | Kelch domain-containing protein 3; May be involved in meiotic recombination process. | 0.720 |
| CUL2 | APPBP2 | ENSBTAP00000070862 | ENSBTAP00000068280 | CUL2 protein; Belongs to the cullin family. | Amyloid beta precursor protein binding protein 2. | 0.748 |
| CUL2 | COMMD1 | ENSBTAP00000070862 | ENSBTAP00000026470 | CUL2 protein; Belongs to the cullin family. | COMM domain-containing protein 1; Proposed scaffold protein that is implicated in diverse physiological processes and whose function may be in part linked to its ability to regulate ubiquitination of specific cellular proteins. Can modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes by displacing CAND1; in vitro promotes CRL E3 activity and dissociates CAND1 from CUL1 and CUL2. Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF- kappa-B activity. Involved in the regulation of membrane expression and ubiquiti [...] | 0.959 |
| CUL2 | FEM1A | ENSBTAP00000070862 | ENSBTAP00000004519 | CUL2 protein; Belongs to the cullin family. | Protein fem-1 homolog A; Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. May participate in antiinflammatory signaling via its interaction with PTGER4 (By similarity); Belongs to the fem-1 family. | 0.899 |
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