STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BCL2A1Bcl-2-related protein A1; Retards apoptosis induced by IL-3 deprivation. May function in the response of hemopoietic cells to external signals and in maintaining endothelial survival during infection (By similarity). Can inhibit apoptosis induced by serum starvation in the mammary epithelial cell line HC11 (By similarity). (175 aa)    
Predicted Functional Partners:
BCL2L11
Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family.
    
 
 0.951
BAK1
Bcl-2 homologous antagonist/killer transcript variant 1.
    
 
 0.947
BID
BH3-interacting domain death agonist; Counters the protective effect of Bcl-2.
   
 
 0.892
PMAIP1
Phorbol-12-myristate-13-acetate-induced protein 1.
    
 
 0.891
BBC3
Uncharacterized protein.
   
 
 0.855
BMF
Bcl2 modifying factor.
    
 
 0.836
BIRC3
Baculoviral IAP repeat-containing 3.
   
 
 0.730
APAF1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 
 0.705
CFLAR
CASP8 and FADD like apoptosis regulator; Belongs to the peptidase C14A family.
   
 
 0.703
BAD
BCL2 associated agonist of cell death.
   
 
 0.650
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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