node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DNAJC17 | NDRG2 | ENSBTAP00000017926 | ENSBTAP00000073589 | DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription. | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | 0.534 |
FDFT1 | NDRG2 | ENSBTAP00000016504 | ENSBTAP00000073589 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family. | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | 0.468 |
IARS2 | NDRG2 | ENSBTAP00000053447 | ENSBTAP00000073589 | Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | 0.424 |
KIAA1143 | NDRG2 | ENSBTAP00000022233 | ENSBTAP00000073589 | Uncharacterized protein KIAA1143 homolog. | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | 0.531 |
NDRG1 | NDRG2 | ENSBTAP00000059646 | ENSBTAP00000073589 | Protein NDRG1; Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking notably of the Schwann cell and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulat [...] | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | 0.562 |
NDRG2 | DNAJC17 | ENSBTAP00000073589 | ENSBTAP00000017926 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | DnaJ homolog subfamily C member 17; May negatively affect PAX8-induced thyroglobulin/TG transcription. | 0.534 |
NDRG2 | FDFT1 | ENSBTAP00000073589 | ENSBTAP00000016504 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family. | 0.468 |
NDRG2 | IARS2 | ENSBTAP00000073589 | ENSBTAP00000053447 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | Isoleucyl-tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.424 |
NDRG2 | KIAA1143 | ENSBTAP00000073589 | ENSBTAP00000022233 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | Uncharacterized protein KIAA1143 homolog. | 0.531 |
NDRG2 | NDRG1 | ENSBTAP00000073589 | ENSBTAP00000059646 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | Protein NDRG1; Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking notably of the Schwann cell and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulat [...] | 0.562 |
NDRG2 | PIANP | ENSBTAP00000073589 | ENSBTAP00000037558 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | PILR alpha associated neural protein. | 0.504 |
NDRG2 | PIBF1 | ENSBTAP00000073589 | ENSBTAP00000044031 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | Progesterone immunomodulatory binding factor 1. | 0.424 |
NDRG2 | PODXL2 | ENSBTAP00000073589 | ENSBTAP00000041120 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | Podocalyxin like 2. | 0.438 |
NDRG2 | PPM1B | ENSBTAP00000073589 | ENSBTAP00000043518 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | Protein phosphatase 1B; Enzyme with a broad specificity. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF- alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB (By similarity). | 0.425 |
NDRG2 | RTN2 | ENSBTAP00000073589 | ENSBTAP00000010770 | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | Reticulon. | 0.498 |
PIANP | NDRG2 | ENSBTAP00000037558 | ENSBTAP00000073589 | PILR alpha associated neural protein. | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | 0.504 |
PIANP | PODXL2 | ENSBTAP00000037558 | ENSBTAP00000041120 | PILR alpha associated neural protein. | Podocalyxin like 2. | 0.662 |
PIBF1 | NDRG2 | ENSBTAP00000044031 | ENSBTAP00000073589 | Progesterone immunomodulatory binding factor 1. | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | 0.424 |
PODXL2 | NDRG2 | ENSBTAP00000041120 | ENSBTAP00000073589 | Podocalyxin like 2. | Protein NDRG2; Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity). | 0.438 |
PODXL2 | PIANP | ENSBTAP00000041120 | ENSBTAP00000037558 | Podocalyxin like 2. | PILR alpha associated neural protein. | 0.662 |