STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TSGA10IPTestis-specific protein 10-interacting protein. (562 aa)    
Predicted Functional Partners:
SPAG5
Sperm associated antigen 5.
      
 0.661
ITIH2
Inter-alpha-trypsin inhibitor heavy chain H2.
      
 0.655
HNRNPAB
Heterogeneous nuclear ribonucleoprotein A/B.
      
 0.622
SLX4IP
Uncharacterized protein.
      
 0.569
HYPK
Huntingtin interacting protein K.
    
   0.483
TEX33
Testis expressed 33.
  
     0.418
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa.
  
     0.414
HIST1H2AG
Histone H2A type 1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
      
 0.412
HIST1H2AG-3
Histone H2A type 1.
      
 0.412
AHSG
Alpha-2-HS-glycoprotein; Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Suggested to have lymphocyte stimulating properties, lipid binding capability and to bind thyroid hormone.
      
 0.410
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.