node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
UBE2A | UBE2E1 | ENSBTAP00000063161 | ENSBTAP00000065694 | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.642 |
UBE2A | UBE2G2 | ENSBTAP00000063161 | ENSBTAP00000055782 | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 G2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). | 0.541 |
UBE2A | UBE2H | ENSBTAP00000063161 | ENSBTAP00000001205 | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 H; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, a core component of the CTLH E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A. | 0.586 |
UBE2A | UBE2J1 | ENSBTAP00000063161 | ENSBTAP00000024529 | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin conjugating enzyme E2 J1. | 0.642 |
UBE2A | UBE2J2 | ENSBTAP00000063161 | ENSBTAP00000069660 | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 J2; Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). Belongs to the ubiquitin-conjugating enzyme family. | 0.607 |
UBE2A | UBE2Q1 | ENSBTAP00000063161 | ENSBTAP00000009889 | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin conjugating enzyme E2 Q1. | 0.754 |
UBE2A | UBE2R2 | ENSBTAP00000063161 | ENSBTAP00000071789 | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.572 |
UBE2A | UBE2S | ENSBTAP00000063161 | ENSBTAP00000058650 | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 S; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiqui [...] | 0.532 |
UBE2A | UBE2Z | ENSBTAP00000063161 | ENSBTAP00000040996 | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin conjugating enzyme E2 Z. | 0.552 |
UBE2E1 | UBE2A | ENSBTAP00000065694 | ENSBTAP00000063161 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | 0.642 |
UBE2E1 | UBE2G2 | ENSBTAP00000065694 | ENSBTAP00000055782 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 G2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). | 0.576 |
UBE2E1 | UBE2H | ENSBTAP00000065694 | ENSBTAP00000001205 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 H; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. E2 ubiquitin conjugating enzyme that transfers ubiquitin to MAEA, a core component of the CTLH E3 ubiquitin-protein ligase complex. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Capable, in vitro, to ubiquitinate histone H2A. | 0.646 |
UBE2E1 | UBE2J1 | ENSBTAP00000065694 | ENSBTAP00000024529 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin conjugating enzyme E2 J1. | 0.600 |
UBE2E1 | UBE2J2 | ENSBTAP00000065694 | ENSBTAP00000069660 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 J2; Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). Belongs to the ubiquitin-conjugating enzyme family. | 0.648 |
UBE2E1 | UBE2Q1 | ENSBTAP00000065694 | ENSBTAP00000009889 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin conjugating enzyme E2 Q1. | 0.801 |
UBE2E1 | UBE2R2 | ENSBTAP00000065694 | ENSBTAP00000071789 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.574 |
UBE2E1 | UBE2S | ENSBTAP00000065694 | ENSBTAP00000058650 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin-conjugating enzyme E2 S; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes 'Lys-11'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating 'Lys-11'-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiqui [...] | 0.831 |
UBE2E1 | UBE2Z | ENSBTAP00000065694 | ENSBTAP00000040996 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | Ubiquitin conjugating enzyme E2 Z. | 0.703 |
UBE2G2 | UBE2A | ENSBTAP00000055782 | ENSBTAP00000063161 | Ubiquitin-conjugating enzyme E2 G2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. | 0.541 |
UBE2G2 | UBE2E1 | ENSBTAP00000055782 | ENSBTAP00000065694 | Ubiquitin-conjugating enzyme E2 G2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD). | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.576 |