node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DAAM1 | DAAM2 | ENSBTAP00000058157 | ENSBTAP00000057936 | Dishevelled associated activator of morphogenesis 1. | Dishevelled associated activator of morphogenesis 2. | 0.903 |
DAAM1 | DVL1 | ENSBTAP00000058157 | ENSBTAP00000014152 | Dishevelled associated activator of morphogenesis 1. | Uncharacterized protein. | 0.942 |
DAAM1 | DVL2 | ENSBTAP00000058157 | ENSBTAP00000057707 | Dishevelled associated activator of morphogenesis 1. | Dishevelled segment polarity protein 2. | 0.974 |
DAAM1 | DVL3 | ENSBTAP00000058157 | ENSBTAP00000025757 | Dishevelled associated activator of morphogenesis 1. | Dishevelled segment polarity protein 3. | 0.954 |
DAAM1 | E1BHJ0_BOVIN | ENSBTAP00000058157 | ENSBTAP00000050051 | Dishevelled associated activator of morphogenesis 1. | Profilin; Belongs to the profilin family. | 0.759 |
DAAM1 | G3MZ01_BOVIN | ENSBTAP00000058157 | ENSBTAP00000054791 | Dishevelled associated activator of morphogenesis 1. | Profilin; Belongs to the profilin family. | 0.759 |
DAAM1 | PFN1 | ENSBTAP00000058157 | ENSBTAP00000006465 | Dishevelled associated activator of morphogenesis 1. | Profilin-1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR (By similarity). | 0.860 |
DAAM1 | PFN2 | ENSBTAP00000058157 | ENSBTAP00000014805 | Dishevelled associated activator of morphogenesis 1. | Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. | 0.760 |
DAAM1 | PFN4 | ENSBTAP00000058157 | ENSBTAP00000004412 | Dishevelled associated activator of morphogenesis 1. | Profilin-4; Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA); Belongs to the profilin family. | 0.869 |
DAAM1 | RHOA | ENSBTAP00000058157 | ENSBTAP00000005600 | Dishevelled associated activator of morphogenesis 1. | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] | 0.984 |
DAAM2 | DAAM1 | ENSBTAP00000057936 | ENSBTAP00000058157 | Dishevelled associated activator of morphogenesis 2. | Dishevelled associated activator of morphogenesis 1. | 0.903 |
DAAM2 | DVL1 | ENSBTAP00000057936 | ENSBTAP00000014152 | Dishevelled associated activator of morphogenesis 2. | Uncharacterized protein. | 0.937 |
DAAM2 | DVL2 | ENSBTAP00000057936 | ENSBTAP00000057707 | Dishevelled associated activator of morphogenesis 2. | Dishevelled segment polarity protein 2. | 0.961 |
DAAM2 | DVL3 | ENSBTAP00000057936 | ENSBTAP00000025757 | Dishevelled associated activator of morphogenesis 2. | Dishevelled segment polarity protein 3. | 0.929 |
DAAM2 | E1BHJ0_BOVIN | ENSBTAP00000057936 | ENSBTAP00000050051 | Dishevelled associated activator of morphogenesis 2. | Profilin; Belongs to the profilin family. | 0.514 |
DAAM2 | G3MZ01_BOVIN | ENSBTAP00000057936 | ENSBTAP00000054791 | Dishevelled associated activator of morphogenesis 2. | Profilin; Belongs to the profilin family. | 0.490 |
DAAM2 | PFN1 | ENSBTAP00000057936 | ENSBTAP00000006465 | Dishevelled associated activator of morphogenesis 2. | Profilin-1; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR (By similarity). | 0.488 |
DAAM2 | PFN2 | ENSBTAP00000057936 | ENSBTAP00000014805 | Dishevelled associated activator of morphogenesis 2. | Profilin-2; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. | 0.539 |
DAAM2 | PFN4 | ENSBTAP00000057936 | ENSBTAP00000004412 | Dishevelled associated activator of morphogenesis 2. | Profilin-4; Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA); Belongs to the profilin family. | 0.742 |
DAAM2 | RHOA | ENSBTAP00000057936 | ENSBTAP00000005600 | Dishevelled associated activator of morphogenesis 2. | Transforming protein RhoA; Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. Mainly associated with cytoskeleton organization, in active state binds to a variety of effector proteins to regulate cellular responses such cytoskeletal dynamics, cell migration and cell cycle. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essent [...] | 0.956 |