node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTBS | FUCA1 | ENSBTAP00000007603 | ENSBTAP00000040572 | Di-N-acetylchitobiase; Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase; Belongs to the glycosyl hydrolase 18 family. | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | 0.429 |
CTBS | MAN2B1 | ENSBTAP00000007603 | ENSBTAP00000064540 | Di-N-acetylchitobiase; Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase; Belongs to the glycosyl hydrolase 18 family. | Lysosomal alpha-mannosidase A peptide; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | 0.752 |
CTBS | MAN2C1 | ENSBTAP00000007603 | ENSBTAP00000009690 | Di-N-acetylchitobiase; Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase; Belongs to the glycosyl hydrolase 18 family. | Mannosidase alpha class 2C member 1. | 0.626 |
CTBS | MANBA | ENSBTAP00000007603 | ENSBTAP00000026334 | Di-N-acetylchitobiase; Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase; Belongs to the glycosyl hydrolase 18 family. | Beta-mannosidase; Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides. | 0.617 |
FUCA1 | CTBS | ENSBTAP00000040572 | ENSBTAP00000007603 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | Di-N-acetylchitobiase; Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase; Belongs to the glycosyl hydrolase 18 family. | 0.429 |
FUCA1 | HGSNAT | ENSBTAP00000040572 | ENSBTAP00000071043 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | Heparan-alpha-glucosaminide N-acetyltransferase. | 0.575 |
FUCA1 | MAN2B1 | ENSBTAP00000040572 | ENSBTAP00000064540 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | Lysosomal alpha-mannosidase A peptide; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | 0.668 |
FUCA1 | MANBA | ENSBTAP00000040572 | ENSBTAP00000026334 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | Beta-mannosidase; Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides. | 0.624 |
FUCA1 | NAGLU | ENSBTAP00000040572 | ENSBTAP00000058243 | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | N-acetyl-alpha-glucosaminidase. | 0.655 |
GBA | MAN2B1 | ENSBTAP00000060772 | ENSBTAP00000064540 | Lysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. [...] | Lysosomal alpha-mannosidase A peptide; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | 0.667 |
GBA | MANBA | ENSBTAP00000060772 | ENSBTAP00000026334 | Lysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. [...] | Beta-mannosidase; Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides. | 0.495 |
GBA | NAGLU | ENSBTAP00000060772 | ENSBTAP00000058243 | Lysosomal acid glucosylceramidase; Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates to the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. [...] | N-acetyl-alpha-glucosaminidase. | 0.606 |
HGSNAT | FUCA1 | ENSBTAP00000071043 | ENSBTAP00000040572 | Heparan-alpha-glucosaminide N-acetyltransferase. | Tissue alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins; Belongs to the glycosyl hydrolase 29 family. | 0.575 |
HGSNAT | MAN2B1 | ENSBTAP00000071043 | ENSBTAP00000064540 | Heparan-alpha-glucosaminide N-acetyltransferase. | Lysosomal alpha-mannosidase A peptide; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | 0.598 |
HGSNAT | NAGLU | ENSBTAP00000071043 | ENSBTAP00000058243 | Heparan-alpha-glucosaminide N-acetyltransferase. | N-acetyl-alpha-glucosaminidase. | 0.836 |
MAN1B1 | MAN1B1-2 | ENSBTAP00000054326 | ENSBTAP00000074421 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.901 |
MAN1B1 | MAN2B1 | ENSBTAP00000054326 | ENSBTAP00000064540 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | Lysosomal alpha-mannosidase A peptide; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | 0.654 |
MAN1B1 | MAN2C1 | ENSBTAP00000054326 | ENSBTAP00000009690 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | Mannosidase alpha class 2C member 1. | 0.627 |
MAN1B1-2 | MAN1B1 | ENSBTAP00000074421 | ENSBTAP00000054326 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | 0.901 |
MAN1B1-2 | MAN2B1 | ENSBTAP00000074421 | ENSBTAP00000064540 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. | Lysosomal alpha-mannosidase A peptide; Necessary for the catabolism of N-linked carbohydrates released during glycoprotein turnover; Belongs to the glycosyl hydrolase 38 family. | 0.640 |