node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIMP2 | FUBP3 | ENSBTAP00000009687 | ENSBTAP00000017383 | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2- mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. | Far upstream element binding protein 3. | 0.600 |
FBXO8 | FUBP3 | ENSBTAP00000008831 | ENSBTAP00000017383 | F-box only protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential). | Far upstream element binding protein 3. | 0.636 |
FBXO8 | LRCH1 | ENSBTAP00000008831 | ENSBTAP00000003856 | F-box only protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential). | Leucine rich repeats and calponin homology domain containing 1. | 0.636 |
FBXO8 | TMEM64 | ENSBTAP00000008831 | ENSBTAP00000043140 | F-box only protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential). | Transmembrane protein 64. | 0.695 |
FUBP3 | AIMP2 | ENSBTAP00000017383 | ENSBTAP00000009687 | Far upstream element binding protein 3. | Aminoacyl tRNA synthase complex-interacting multifunctional protein 2; Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2- mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor. | 0.600 |
FUBP3 | FBXO8 | ENSBTAP00000017383 | ENSBTAP00000008831 | Far upstream element binding protein 3. | F-box only protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential). | 0.636 |
FUBP3 | LRCH1 | ENSBTAP00000017383 | ENSBTAP00000003856 | Far upstream element binding protein 3. | Leucine rich repeats and calponin homology domain containing 1. | 0.632 |
FUBP3 | PRRC2A | ENSBTAP00000017383 | ENSBTAP00000026236 | Far upstream element binding protein 3. | Proline rich coiled-coil 2A. | 0.618 |
FUBP3 | PRRC2C | ENSBTAP00000017383 | ENSBTAP00000002380 | Far upstream element binding protein 3. | Proline rich coiled-coil 2C. | 0.630 |
FUBP3 | PUF60 | ENSBTAP00000017383 | ENSBTAP00000061124 | Far upstream element binding protein 3. | Poly(U)-binding-splicing factor PUF60; DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3'-splice si [...] | 0.912 |
FUBP3 | QKI | ENSBTAP00000017383 | ENSBTAP00000048511 | Far upstream element binding protein 3. | Protein quaking; RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation. Required to protect and promote stability of mRNAs such as MBP and CDKN1B which promotes oligodendrocyte differentiation. Participates in mRNA transport by regulating the nuclear export of MBP mRNA. Also involved in regulation of mRNA splicing of MAG pre-mRNA. Acts as a translational repressor (By similarity). | 0.681 |
FUBP3 | SEC16A | ENSBTAP00000017383 | ENSBTAP00000040372 | Far upstream element binding protein 3. | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. | 0.610 |
FUBP3 | TMEM64 | ENSBTAP00000017383 | ENSBTAP00000043140 | Far upstream element binding protein 3. | Transmembrane protein 64. | 0.645 |
FUBP3 | UBAP2L | ENSBTAP00000017383 | ENSBTAP00000049378 | Far upstream element binding protein 3. | Ubiquitin associated protein 2 like. | 0.607 |
LRCH1 | FBXO8 | ENSBTAP00000003856 | ENSBTAP00000008831 | Leucine rich repeats and calponin homology domain containing 1. | F-box only protein 8; May promote guanine-nucleotide exchange on an ARF. Promotes the activation of ARF through replacement of GDP with GTP (Potential). | 0.636 |
LRCH1 | FUBP3 | ENSBTAP00000003856 | ENSBTAP00000017383 | Leucine rich repeats and calponin homology domain containing 1. | Far upstream element binding protein 3. | 0.632 |
LRCH1 | TMEM64 | ENSBTAP00000003856 | ENSBTAP00000043140 | Leucine rich repeats and calponin homology domain containing 1. | Transmembrane protein 64. | 0.705 |
PRRC2A | FUBP3 | ENSBTAP00000026236 | ENSBTAP00000017383 | Proline rich coiled-coil 2A. | Far upstream element binding protein 3. | 0.618 |
PRRC2A | PRRC2C | ENSBTAP00000026236 | ENSBTAP00000002380 | Proline rich coiled-coil 2A. | Proline rich coiled-coil 2C. | 0.701 |
PRRC2A | SEC16A | ENSBTAP00000026236 | ENSBTAP00000040372 | Proline rich coiled-coil 2A. | Protein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. | 0.686 |