STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRS3Fibroblast growth factor receptor substrate 3. (495 aa)    
Predicted Functional Partners:
FGFR2
Fibroblast growth factor receptor.
    
 0.854
GRB2
Growth factor receptor-bound protein 2.
    
 0.833
FGFR1
Fibroblast growth factor receptor.
    
 0.771
FGFR4
Fibroblast growth factor receptor.
    
 0.769
FGFR3
Fibroblast growth factor receptor.
    
 0.765
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
    
 0.750
LETM2
Leucine zipper and EF-hand containing transmembrane protein 2.
      
 0.665
ALK
Tyrosine-protein kinase receptor.
    
 
 0.648
FGFRL1
Fibroblast growth factor receptor like 1.
    
 
 0.638
PPP2R2C
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.
   
 
 0.576
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.