node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CLCN6 | OSTM1 | ENSBTAP00000027587 | ENSBTAP00000064390 | Chloride channel protein. | Osteoclastogenesis associated transmembrane protein 1. | 0.761 |
CLCN7 | OSTM1 | ENSBTAP00000021122 | ENSBTAP00000064390 | H(+)/Cl(-) exchange transporter 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen (By similarity). Belongs to the chloride channel (TC 2.A.49) family. ClC- 7/CLCN7 subfamily. | Osteoclastogenesis associated transmembrane protein 1. | 0.999 |
CLCN7 | PLEKHM1 | ENSBTAP00000021122 | ENSBTAP00000067757 | H(+)/Cl(-) exchange transporter 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen (By similarity). Belongs to the chloride channel (TC 2.A.49) family. ClC- 7/CLCN7 subfamily. | Pleckstrin homology and RUN domain containing M1. | 0.755 |
CLCN7 | TCIRG1 | ENSBTAP00000021122 | ENSBTAP00000000367 | H(+)/Cl(-) exchange transporter 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen (By similarity). Belongs to the chloride channel (TC 2.A.49) family. ClC- 7/CLCN7 subfamily. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.813 |
MSANTD1 | OSTM1 | ENSBTAP00000004915 | ENSBTAP00000064390 | Myb/SANT DNA binding domain containing 1. | Osteoclastogenesis associated transmembrane protein 1. | 0.799 |
OSTM1 | CLCN6 | ENSBTAP00000064390 | ENSBTAP00000027587 | Osteoclastogenesis associated transmembrane protein 1. | Chloride channel protein. | 0.761 |
OSTM1 | CLCN7 | ENSBTAP00000064390 | ENSBTAP00000021122 | Osteoclastogenesis associated transmembrane protein 1. | H(+)/Cl(-) exchange transporter 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen (By similarity). Belongs to the chloride channel (TC 2.A.49) family. ClC- 7/CLCN7 subfamily. | 0.999 |
OSTM1 | MSANTD1 | ENSBTAP00000064390 | ENSBTAP00000004915 | Osteoclastogenesis associated transmembrane protein 1. | Myb/SANT DNA binding domain containing 1. | 0.799 |
OSTM1 | PLEKHM1 | ENSBTAP00000064390 | ENSBTAP00000067757 | Osteoclastogenesis associated transmembrane protein 1. | Pleckstrin homology and RUN domain containing M1. | 0.798 |
OSTM1 | QTRT1 | ENSBTAP00000064390 | ENSBTAP00000057388 | Osteoclastogenesis associated transmembrane protein 1. | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] | 0.828 |
OSTM1 | TCIRG1 | ENSBTAP00000064390 | ENSBTAP00000000367 | Osteoclastogenesis associated transmembrane protein 1. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.797 |
OSTM1 | TMED6 | ENSBTAP00000064390 | ENSBTAP00000010015 | Osteoclastogenesis associated transmembrane protein 1. | Transmembrane emp24 domain-containing protein 6. | 0.775 |
OSTM1 | TRABD | ENSBTAP00000064390 | ENSBTAP00000061649 | Osteoclastogenesis associated transmembrane protein 1. | TraB domain-containing protein. | 0.837 |
OSTM1 | TTC7B | ENSBTAP00000064390 | ENSBTAP00000061762 | Osteoclastogenesis associated transmembrane protein 1. | Tetratricopeptide repeat domain 7B. | 0.759 |
OSTM1 | WDYHV1 | ENSBTAP00000064390 | ENSBTAP00000013086 | Osteoclastogenesis associated transmembrane protein 1. | Protein N-terminal glutamine amidohydrolase; Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested sec [...] | 0.828 |
PLEKHM1 | CLCN7 | ENSBTAP00000067757 | ENSBTAP00000021122 | Pleckstrin homology and RUN domain containing M1. | H(+)/Cl(-) exchange transporter 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen (By similarity). Belongs to the chloride channel (TC 2.A.49) family. ClC- 7/CLCN7 subfamily. | 0.755 |
PLEKHM1 | OSTM1 | ENSBTAP00000067757 | ENSBTAP00000064390 | Pleckstrin homology and RUN domain containing M1. | Osteoclastogenesis associated transmembrane protein 1. | 0.798 |
PLEKHM1 | TCIRG1 | ENSBTAP00000067757 | ENSBTAP00000000367 | Pleckstrin homology and RUN domain containing M1. | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. | 0.730 |
QTRT1 | OSTM1 | ENSBTAP00000057388 | ENSBTAP00000064390 | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] | Osteoclastogenesis associated transmembrane protein 1. | 0.828 |
QTRT1 | TMED6 | ENSBTAP00000057388 | ENSBTAP00000010015 | Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] | Transmembrane emp24 domain-containing protein 6. | 0.538 |