STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (631 aa)    
Predicted Functional Partners:
GLIS2
GLIS family zinc finger 2.
   
 
 0.719
ABLIM2
Actin binding LIM protein family member 2.
   
  
 0.704
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor.
   
 
 0.701
NCOR2
Nuclear receptor corepressor 2.
   
 
 0.643
POLR2E
DNA-directed RNA polymerases I, II, and III subunit RPABC1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2E/RPB5 is part of the [...]
    
 
 0.626
ARHGEF39
Rho guanine nucleotide exchange factor 39; Promotes cell proliferation.
      
 0.623
GALNS
Galactosamine (N-acetyl)-6-sulfatase.
      
 0.593
PRSS57
Serine protease 57; Belongs to the peptidase S1 family.
    
 
 0.590
NCOR1
Nuclear receptor corepressor 1.
   
 
 0.590
GATA1
GATA binding protein 1.
    
 
 0.584
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.