node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASB2 | RARA | ENSBTAP00000063504 | ENSBTAP00000061984 | Ankyrin repeat and SOCS box protein 2; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | Retinoic acid receptor alpha. | 0.749 |
MED1 | NCOR1 | ENSBTAP00000053186 | ENSBTAP00000053758 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 1. | 0.653 |
MED1 | NCOR2 | ENSBTAP00000053186 | ENSBTAP00000060821 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Nuclear receptor corepressor 2. | 0.693 |
MED1 | RARA | ENSBTAP00000053186 | ENSBTAP00000061984 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoic acid receptor alpha. | 0.784 |
MED1 | RARS1 | ENSBTAP00000053186 | ENSBTAP00000019475 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1. | 0.507 |
MED1 | RXRA | ENSBTAP00000053186 | ENSBTAP00000023729 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor alpha. | 0.892 |
MED1 | RXRB | ENSBTAP00000053186 | ENSBTAP00000000860 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoid X receptor, beta. | 0.851 |
MED1 | RXRG | ENSBTAP00000053186 | ENSBTAP00000022350 | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). | 0.883 |
NCOR1 | MED1 | ENSBTAP00000053758 | ENSBTAP00000053186 | Nuclear receptor corepressor 1. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.653 |
NCOR1 | NCOR2 | ENSBTAP00000053758 | ENSBTAP00000060821 | Nuclear receptor corepressor 1. | Nuclear receptor corepressor 2. | 0.961 |
NCOR1 | RARA | ENSBTAP00000053758 | ENSBTAP00000061984 | Nuclear receptor corepressor 1. | Retinoic acid receptor alpha. | 0.834 |
NCOR1 | RARS1 | ENSBTAP00000053758 | ENSBTAP00000019475 | Nuclear receptor corepressor 1. | Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1. | 0.600 |
NCOR1 | RXRA | ENSBTAP00000053758 | ENSBTAP00000023729 | Nuclear receptor corepressor 1. | Retinoid X receptor alpha. | 0.910 |
NCOR1 | RXRB | ENSBTAP00000053758 | ENSBTAP00000000860 | Nuclear receptor corepressor 1. | Retinoid X receptor, beta. | 0.869 |
NCOR1 | RXRG | ENSBTAP00000053758 | ENSBTAP00000022350 | Nuclear receptor corepressor 1. | Retinoic acid receptor RXR-gamma; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity). | 0.869 |
NCOR1 | ZBTB16 | ENSBTAP00000053758 | ENSBTAP00000014968 | Nuclear receptor corepressor 1. | Zinc finger and BTB domain containing 16. | 0.734 |
NCOR2 | MED1 | ENSBTAP00000060821 | ENSBTAP00000053186 | Nuclear receptor corepressor 2. | Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. | 0.693 |
NCOR2 | NCOR1 | ENSBTAP00000060821 | ENSBTAP00000053758 | Nuclear receptor corepressor 2. | Nuclear receptor corepressor 1. | 0.961 |
NCOR2 | RARA | ENSBTAP00000060821 | ENSBTAP00000061984 | Nuclear receptor corepressor 2. | Retinoic acid receptor alpha. | 0.767 |
NCOR2 | RARS1 | ENSBTAP00000060821 | ENSBTAP00000019475 | Nuclear receptor corepressor 2. | Arginine--tRNA ligase, cytoplasmic; Forms part of a macromolecular complex that catalyzes the attachment of specific amino acids to cognate tRNAs during protein synthesis. Modulates the secretion of AIMP1 and may be involved in generation of the inflammatory cytokine EMAP2 from AIMP1. | 0.547 |