node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACER3 | CERS2 | ENSBTAP00000051467 | ENSBTAP00000058510 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | 0.971 |
ACER3 | CERS3 | ENSBTAP00000051467 | ENSBTAP00000052564 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | Ceramide synthase 3. | 0.964 |
ACER3 | CERS4 | ENSBTAP00000051467 | ENSBTAP00000004459 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | Ceramide synthase 4; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor. | 0.973 |
ACER3 | CERS5 | ENSBTAP00000051467 | ENSBTAP00000059173 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | Ceramide synthase 5. | 0.971 |
ACER3 | CERS6 | ENSBTAP00000051467 | ENSBTAP00000071330 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | Ceramide synthase 6. | 0.971 |
ACER3 | DEGS1 | ENSBTAP00000051467 | ENSBTAP00000016887 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | Sphingolipid delta(4)-desaturase DES1; Has sphingolipid-delta-4-desaturase activity. Converts D- erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (By similarity); Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. | 0.967 |
ACER3 | KDSR | ENSBTAP00000051467 | ENSBTAP00000010155 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | 3-ketodihydrosphingosine reductase; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.950 |
ACER3 | SMPD2 | ENSBTAP00000051467 | ENSBTAP00000010706 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | Sphingomyelin phosphodiesterase 2. | 0.731 |
ACER3 | SMPD4 | ENSBTAP00000051467 | ENSBTAP00000029373 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | Sphingomyelin phosphodiesterase 4. | 0.580 |
ACER3 | UGCG | ENSBTAP00000051467 | ENSBTAP00000041368 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | UDP-glucose ceramide glucosyltransferase. | 0.515 |
CERS2 | ACER3 | ENSBTAP00000058510 | ENSBTAP00000051467 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. | 0.971 |
CERS2 | CERS3 | ENSBTAP00000058510 | ENSBTAP00000052564 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | Ceramide synthase 3. | 0.906 |
CERS2 | CERS4 | ENSBTAP00000058510 | ENSBTAP00000004459 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | Ceramide synthase 4; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor. | 0.910 |
CERS2 | CERS5 | ENSBTAP00000058510 | ENSBTAP00000059173 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | Ceramide synthase 5. | 0.920 |
CERS2 | CERS6 | ENSBTAP00000058510 | ENSBTAP00000071330 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | Ceramide synthase 6. | 0.920 |
CERS2 | DEGS1 | ENSBTAP00000058510 | ENSBTAP00000016887 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | Sphingolipid delta(4)-desaturase DES1; Has sphingolipid-delta-4-desaturase activity. Converts D- erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine) (By similarity); Belongs to the fatty acid desaturase type 1 family. DEGS subfamily. | 0.978 |
CERS2 | KDSR | ENSBTAP00000058510 | ENSBTAP00000010155 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | 3-ketodihydrosphingosine reductase; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.977 |
CERS2 | SMPD2 | ENSBTAP00000058510 | ENSBTAP00000010706 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | Sphingomyelin phosphodiesterase 2. | 0.898 |
CERS2 | SMPD4 | ENSBTAP00000058510 | ENSBTAP00000029373 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | Sphingomyelin phosphodiesterase 4. | 0.863 |
CERS2 | UGCG | ENSBTAP00000058510 | ENSBTAP00000041368 | Ceramide synthase 2; Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward very- long (C22:0-C24:0) chain as acyl donor. | UDP-glucose ceramide glucosyltransferase. | 0.963 |