node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYP2E1 | CYP2J2 | ENSBTAP00000024437 | ENSBTAP00000052728 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.918 |
CYP2E1 | CYP2U1 | ENSBTAP00000024437 | ENSBTAP00000017246 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Cytochrome P450 2U1; A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Acts as an omega and omega-1 hydroxylase for arachidonic acid and possibly for other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. May downregulate [...] | 0.923 |
CYP2E1 | CYP4A11 | ENSBTAP00000024437 | ENSBTAP00000048143 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.951 |
CYP2E1 | CYP4A22 | ENSBTAP00000024437 | ENSBTAP00000000280 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | CYP4A22 protein; Belongs to the cytochrome P450 family. | 0.937 |
CYP2E1 | CYP4F2 | ENSBTAP00000024437 | ENSBTAP00000058368 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.942 |
CYP2E1 | CYP4F2-2 | ENSBTAP00000024437 | ENSBTAP00000072588 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.942 |
CYP2E1 | LOC100295883 | ENSBTAP00000024437 | ENSBTAP00000071843 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.934 |
CYP2E1 | LOC509506 | ENSBTAP00000024437 | ENSBTAP00000036224 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.934 |
CYP2E1 | LOC534967 | ENSBTAP00000024437 | ENSBTAP00000055004 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Uncharacterized protein. | 0.931 |
CYP2E1 | LOC784417 | ENSBTAP00000024437 | ENSBTAP00000021785 | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.932 |
CYP2J2 | CYP2E1 | ENSBTAP00000052728 | ENSBTAP00000024437 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics. | 0.918 |
CYP2J2 | CYP2U1 | ENSBTAP00000052728 | ENSBTAP00000017246 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Cytochrome P450 2U1; A cytochrome P450 monooxygenase involved in the metabolism of arachidonic acid and its conjugates. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Acts as an omega and omega-1 hydroxylase for arachidonic acid and possibly for other long chain fatty acids. May modulate the arachidonic acid signaling pathway and play a role in other fatty acid signaling processes. May downregulate [...] | 0.924 |
CYP2J2 | CYP4A11 | ENSBTAP00000052728 | ENSBTAP00000048143 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.950 |
CYP2J2 | CYP4A22 | ENSBTAP00000052728 | ENSBTAP00000000280 | Uncharacterized protein; Belongs to the cytochrome P450 family. | CYP4A22 protein; Belongs to the cytochrome P450 family. | 0.945 |
CYP2J2 | CYP4F2 | ENSBTAP00000052728 | ENSBTAP00000058368 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.947 |
CYP2J2 | CYP4F2-2 | ENSBTAP00000052728 | ENSBTAP00000072588 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.945 |
CYP2J2 | LOC100295883 | ENSBTAP00000052728 | ENSBTAP00000071843 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.931 |
CYP2J2 | LOC509506 | ENSBTAP00000052728 | ENSBTAP00000036224 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.931 |
CYP2J2 | LOC534967 | ENSBTAP00000052728 | ENSBTAP00000055004 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Uncharacterized protein. | 0.931 |
CYP2J2 | LOC784417 | ENSBTAP00000052728 | ENSBTAP00000021785 | Uncharacterized protein; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the cytochrome P450 family. | 0.933 |