STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GAB3GRB2 associated binding protein 3. (585 aa)    
Predicted Functional Partners:
GRB2
Growth factor receptor-bound protein 2.
    
 
 0.723
SLC16A2
Solute carrier family 16 member 2.
      
 0.651
CRK
CRK proto-oncogene, adaptor protein.
      
 0.649
BCO1
Beta-carotene oxygenase 1.
      
 0.621
CA7
Carbonic anhydrase 7; Belongs to the alpha-carbonic anhydrase family.
      
 0.601
OGT
TPR_REGION domain-containing protein.
      
 0.521
RPS4X
40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.
      
 0.483
CELA2A
Chymotrypsin-like elastase family member 2A; Acts upon elastin; Belongs to the peptidase S1 family. Elastase subfamily.
      
 0.483
MECP2
Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
   
  
 0.479
UNK
Unk zinc finger.
      
 0.479
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.