node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CARS2 | PIGL | ENSBTAP00000068554 | ENSBTAP00000017653 | Cysteine--tRNA ligase, mitochondrial. | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol (By similarity); Belongs to the PIGL family. | 0.871 |
DPM2 | G1K1P6_BOVIN | ENSBTAP00000004393 | ENSBTAP00000018063 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | Uncharacterized protein. | 0.942 |
DPM2 | PIGA | ENSBTAP00000004393 | ENSBTAP00000066131 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | Phosphatidylinositol glycan anchor biosynthesis class A. | 0.993 |
DPM2 | PIGC | ENSBTAP00000004393 | ENSBTAP00000034036 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | 0.997 |
DPM2 | PIGH | ENSBTAP00000004393 | ENSBTAP00000024352 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | Phosphatidylinositol N-acetylglucosaminyltransferase subunit H; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | 0.998 |
DPM2 | PIGL | ENSBTAP00000004393 | ENSBTAP00000017653 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol (By similarity); Belongs to the PIGL family. | 0.980 |
DPM2 | PIGM | ENSBTAP00000004393 | ENSBTAP00000003140 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly (By similarity). | 0.931 |
DPM2 | PIGP | ENSBTAP00000004393 | ENSBTAP00000071764 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | 0.996 |
DPM2 | PIGW | ENSBTAP00000004393 | ENSBTAP00000045720 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI- anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. | 0.678 |
G1K1P6_BOVIN | DPM2 | ENSBTAP00000018063 | ENSBTAP00000004393 | Uncharacterized protein. | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | 0.942 |
G1K1P6_BOVIN | PIGA | ENSBTAP00000018063 | ENSBTAP00000066131 | Uncharacterized protein. | Phosphatidylinositol glycan anchor biosynthesis class A. | 0.956 |
G1K1P6_BOVIN | PIGC | ENSBTAP00000018063 | ENSBTAP00000034036 | Uncharacterized protein. | Phosphatidylinositol N-acetylglucosaminyltransferase subunit C; Involved in GPI anchor biosynthesis. Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N- acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | 0.900 |
G1K1P6_BOVIN | PIGH | ENSBTAP00000018063 | ENSBTAP00000024352 | Uncharacterized protein. | Phosphatidylinositol N-acetylglucosaminyltransferase subunit H; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | 0.940 |
G1K1P6_BOVIN | PIGL | ENSBTAP00000018063 | ENSBTAP00000017653 | Uncharacterized protein. | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol (By similarity); Belongs to the PIGL family. | 0.943 |
G1K1P6_BOVIN | PIGP | ENSBTAP00000018063 | ENSBTAP00000071764 | Uncharacterized protein. | Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis. | 0.923 |
G1K1P6_BOVIN | PIGW | ENSBTAP00000018063 | ENSBTAP00000045720 | Uncharacterized protein. | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI- anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. | 0.606 |
GPLD1 | PIGL | ENSBTAP00000006557 | ENSBTAP00000017653 | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane. | N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; Involved in the second step of GPI biosynthesis. De-N- acetylation of N-acetylglucosaminyl-phosphatidylinositol (By similarity); Belongs to the PIGL family. | 0.914 |
GPLD1 | PIGW | ENSBTAP00000006557 | ENSBTAP00000045720 | Phosphatidylinositol-glycan-specific phospholipase D; This protein hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans (GPI-anchor) thus releasing these proteins from the membrane. | Phosphatidylinositol-glycan biosynthesis class W protein; Required for the transport of GPI-anchored proteins to the plasma membrane. Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI- anchor. Acetylation during GPI-anchor biosynthesis is not essential for the subsequent mannosylation and is usually removed soon after the attachment of GPIs to proteins. | 0.923 |
PIGA | DPM2 | ENSBTAP00000066131 | ENSBTAP00000004393 | Phosphatidylinositol glycan anchor biosynthesis class A. | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulates the biosynthesis of dolichol phosphate-mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity (By similarity). Belongs to the DPM2 family. | 0.993 |
PIGA | G1K1P6_BOVIN | ENSBTAP00000066131 | ENSBTAP00000018063 | Phosphatidylinositol glycan anchor biosynthesis class A. | Uncharacterized protein. | 0.956 |