STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTDSPLFCP1 homology domain-containing protein. (292 aa)    
Predicted Functional Partners:
PPP1R7
Protein phosphatase 1 regulatory subunit 7; Regulatory subunit of protein phosphatase 1. Inactivates the PPP1CC isoform 2 during epididymal sperm maturation. Belongs to the SDS22 family.
 
      0.744
CDCA3
Cell division cycle associated 3.
    
 
 0.635
VILL
Villin like.
 
  
 
 0.633
CTDSP1
CTD small phosphatase 1.
  
 
 
0.623
MBP
Myelin basic protein; Is, with PLP, the most abundant protein component of the myelin membrane in the CNS. Has a role in both the formation and stabilization of this compact multilayer arrangement of bilayers. Each splice variant and charge isomer may have a specialized function in the assembly of an optimized, biochemically functional myelin membrane (By similarity).
    
 
 0.618
GTF2F1
General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family.
   
 
 0.617
BSPRY
B-box and SPRY domain containing.
    
 
 0.605
REST
Uncharacterized protein.
    
 
 0.605
PXDC1
PX domain-containing protein 1.
      
 0.604
EMC8
ER membrane protein complex subunit 8; Belongs to the EMC8/EMC9 family.
   
  
 0.603
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.