STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TOR2ATorsin-2A. (321 aa)    
Predicted Functional Partners:
PPP1R26
Protein phosphatase 1 regulatory subunit 26.
      
 0.802
GPR152
G protein-coupled receptor 152.
    
 
 0.779
PTRH1
Peptidyl-tRNA hydrolase 1 homolog.
 
 
  
 0.740
TMEM134
Transmembrane protein 134.
      
 0.732
SLC25A27
Solute carrier family 25 member 27; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.728
RNF170
E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase. Plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells.
      
 0.728
TAC4
Uncharacterized protein.
      
 0.689
BTBD1
BTB domain containing 1.
      
 0.685
PITPNM1
Phosphatidylinositol transfer protein membrane associated 1.
    
 
 0.680
CABP4
Calcium-binding protein 4; May play a role in normal synaptic function, probably through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1F, shifting the activation range to more hyperpolarized voltages (By similarity).
      
 0.676
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.