node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MVB12A | MVB12B | ENSBTAP00000005111 | ENSBTAP00000060863 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Multivesicular body subunit 12B. | 0.923 |
MVB12A | UBAP1 | ENSBTAP00000005111 | ENSBTAP00000073370 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Ubiquitin associated protein 1. | 0.912 |
MVB12A | UEVLD | ENSBTAP00000005111 | ENSBTAP00000018040 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | UEV and lactate/malate dehyrogenase domains. | 0.865 |
MVB12A | VPS28 | ENSBTAP00000005111 | ENSBTAP00000056763 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. | 0.993 |
MVB12A | VPS36 | ENSBTAP00000005111 | ENSBTAP00000005646 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Vacuolar protein-sorting-associated protein 36; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may a [...] | 0.861 |
MVB12A | VPS37A | ENSBTAP00000005111 | ENSBTAP00000013675 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | Vacuolar protein sorting 37 homolog A (S. cerevisiae). | 0.965 |
MVB12A | VPS37B | ENSBTAP00000005111 | ENSBTAP00000073474 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | VPS37 C-terminal domain-containing protein. | 0.986 |
MVB12A | VPS37C | ENSBTAP00000005111 | ENSBTAP00000010607 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | VPS37C subunit of ESCRT-I. | 0.958 |
MVB12A | VPS37D | ENSBTAP00000005111 | ENSBTAP00000011185 | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | VPS37D subunit of ESCRT-I. | 0.951 |
MVB12B | MVB12A | ENSBTAP00000060863 | ENSBTAP00000005111 | Multivesicular body subunit 12B. | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | 0.923 |
MVB12B | UBAP1 | ENSBTAP00000060863 | ENSBTAP00000073370 | Multivesicular body subunit 12B. | Ubiquitin associated protein 1. | 0.757 |
MVB12B | UEVLD | ENSBTAP00000060863 | ENSBTAP00000018040 | Multivesicular body subunit 12B. | UEV and lactate/malate dehyrogenase domains. | 0.911 |
MVB12B | VPS28 | ENSBTAP00000060863 | ENSBTAP00000056763 | Multivesicular body subunit 12B. | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. | 0.981 |
MVB12B | VPS36 | ENSBTAP00000060863 | ENSBTAP00000005646 | Multivesicular body subunit 12B. | Vacuolar protein-sorting-associated protein 36; Component of the ESCRT-II complex (endosomal sorting complex required for transport II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. Its ability to bind ubiquitin probably plays a role in endosomal sorting of ubiquitinated cargo proteins by ESCRT complexes. The ESCRT-II complex may a [...] | 0.700 |
MVB12B | VPS37A | ENSBTAP00000060863 | ENSBTAP00000013675 | Multivesicular body subunit 12B. | Vacuolar protein sorting 37 homolog A (S. cerevisiae). | 0.969 |
MVB12B | VPS37B | ENSBTAP00000060863 | ENSBTAP00000073474 | Multivesicular body subunit 12B. | VPS37 C-terminal domain-containing protein. | 0.978 |
MVB12B | VPS37C | ENSBTAP00000060863 | ENSBTAP00000010607 | Multivesicular body subunit 12B. | VPS37C subunit of ESCRT-I. | 0.945 |
MVB12B | VPS37D | ENSBTAP00000060863 | ENSBTAP00000011185 | Multivesicular body subunit 12B. | VPS37D subunit of ESCRT-I. | 0.947 |
SPTY2D1 | UEVLD | ENSBTAP00000002177 | ENSBTAP00000018040 | SPT2 chromatin protein domain containing 1. | UEV and lactate/malate dehyrogenase domains. | 0.885 |
UBAP1 | MVB12A | ENSBTAP00000073370 | ENSBTAP00000005111 | Ubiquitin associated protein 1. | Multivesicular body subunit 12A; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity); Belongs to the MVB12 family. | 0.912 |