STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SP2Transcription factor Sp2; Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. (606 aa)    
Predicted Functional Partners:
FANCD2OS
FANCD2 opposite strand protein.
      
 0.745
WAC
WW domain containing adaptor with coiled-coil.
    
 
 0.711
TRIML1
Tripartite motif family like 1.
    
 
 0.600
ZNF263
Zinc finger protein 263.
    
 
0.519
KSR2
Kinase suppressor of ras 2.
    
 
 0.514
POLH
DNA polymerase eta.
      
 0.480
MORN1
MORN repeat containing 1.
    
 
 0.442
PLPP7
acidPPc domain-containing protein.
      
 0.442
RS1
Retinoschisin 1.
    
 
 0.441
MYO5B
Myosin VB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
    
 
 0.440
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos bovis, Bos primigenius taurus, Bovidae sp. Adi Nefas, bovine, cattle, cow, dairy cow, domestic cattle, domestic cow
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